@article {9504,
	title = {{Early-onset Alzheimer{\textquoteright}s disease explained by polygenic risk of late-onset disease?},
	journal = {Alzheimers Dement (Amst)},
	volume = {15},
	year = {2023},
	pages = {e12482},
	abstract = {There is a unique genetic architecture of early- versus late-onset Alzheimer{\textquoteright}s disease (AD).Late-onset AD polygenic risk is not an explanation for early-onset AD.Polygenic risk of late-onset AD does not predict early-onset AD biology.Unique genetic architecture of early- versus late-onset AD parallels AD heterogeneity.},
	author = {Mantyh, W. G. and Cochran, J. N. and Taylor, J. W. and Broce, I. J. and Geier, E. G. and Bonham, L. W. and Anderson, A. G. and Sirkis, D. W. and Joie, R. and Iaccarino, L. and Chaudhary, K. and Edwards, L. and Strom, A. and Grant, H. and Allen, I. E. and Miller, Z. A. and Gorno-Tempini, M. L. and Kramer, J. H. and Miller, B. L. and Desikan, R. S. and Rabinovici, G. D. and Yokoyama, J. S.}
}
