@article {8514,
	title = {{New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders},
	journal = {Nat Hum Behav},
	volume = {3},
	year = {2019},
	month = {09},
	pages = {950{\textendash}961},
	abstract = {Excessive alcohol consumption is one of the main causes of death and disability worldwide. Alcohol consumption is a heritable complex trait. Here we conducted a meta-analysis of genome-wide association studies of alcohol consumption (g d-1) from the UK Biobank, the Alcohol Genome-Wide Consortium and the Cohorts for Heart and Aging Research in Genomic Epidemiology Plus consortia, collecting data from 480,842 people of European descent to decipher the genetic architecture of alcohol intake. We identified 46 new common loci and investigated their potential functional importance using magnetic resonance imaging data and gene expression studies. We identify genetic pathways associated with alcohol consumption and suggest genetic mechanisms that are shared with neuropsychiatric disorders such as schizophrenia.},
	author = {Evangelou, E. and Gao, H. and Chu, C. and Ntritsos, G. and Blakeley, P. and Butts, A. R. and Pazoki, R. and Suzuki, H. and Koskeridis, F. and Yiorkas, A. M. and Karaman, I. and Elliott, J. and Luo, Q. and Aeschbacher, S. and Bartz, T. M. and Baumeister, S. E. and Braund, P. S. and Brown, M. R. and Brody, J. A. and Clarke, T. K. and Dimou, N. and Faul, J. D. and Homuth, G. and Jackson, A. U. and Kentistou, K. A. and Joshi, P. K. and Lemaitre, R. N. and Lind, P. A. and Lyytik?inen, L. P. and Mangino, M. and Milaneschi, Y. and Nelson, C. P. and Nolte, I. M. and Per?l?, M. M. and Polasek, O. and Porteous, D. and Ratliff, S. M. and Smith, J. A. and Stan??kov?, A. and Teumer, A. and Tuominen, S. and Th?riault, S. and Vangipurapu, J. and Whitfield, J. B. and Wood, A. and Yao, J. and Yu, B. and Zhao, W. and Arking, D. E. and Auvinen, J. and Liu, C. and M?nnikk?, M. and Risch, L. and Rotter, J. I. and Snieder, H. and Veijola, J. and Blakemore, A. I. and Boehnke, M. and Campbell, H. and Conen, D. and Eriksson, J. G. and Grabe, H. J. and Guo, X. and van der Harst, P. and Hartman, C. A. and Hayward, C. and Heath, A. C. and Jarvelin, M. R. and K?h?nen, M. and Kardia, S. L. R. and K?hne, M. and Kuusisto, J. and Laakso, M. and Lahti, J. and Lehtim?ki, T. and McIntosh, A. M. and Mohlke, K. L. and Morrison, A. C. and Martin, N. G. and Oldehinkel, A. J. and Penninx, B. W. J. H. and Psaty, B. M. and Raitakari, O. T. and Rudan, I. and Samani, N. J. and Scott, L. J. and Spector, T. D. and Verweij, N. and Weir, D. R. and Wilson, J. F. and Levy, D. and Tzoulaki, I. and Bell, J. D. and Matthews, P. M. and Rothenfluh, A. and Desrivi?res, S. and Schumann, G. and Elliott, P.}
}
