01829nas a2200229 4500008004100000022001400041245014800055210006900203260001300272300001200285490000700297520109200304100001901396700002101415700002101436700002401457700002101481700002301502700001801525700002001543856003601563 2014 eng d a1552-688700aAssociation Between 6-Minute Walk Test and All-Cause Mortality, Coronary Heart Disease-Specific Mortality, and Incident Coronary Heart Disease.0 aAssociation Between 6Minute Walk Test and AllCause Mortality Cor c2014 Jun a583-5990 v263 a

OBJECTIVE: To examine the association between 6-min walk test (6 MWT) performance and all-cause mortality, coronary heart disease mortality, and incident coronary heart disease in older adults.

METHOD: We conducted a time-to-event analysis of 1,665 Cardiovascular Health Study participants without prevalent cardiovascular disease with a 6 MWT.

RESULTS: During a mean follow-up of 8 years, there were 305 incident coronary heart disease events, and 504 deaths of which 100 were coronary heart disease-related deaths. The 6 MWT performance in the shortest two distance quintiles was associated with increased risk of all-cause mortality (290-338 m: hazard ratio [HR] = 1.7; 95% confidence interval [CI] = [1.2, 2.5]; <290 m: HR = 2.1; 95% CI = [1.4, 3.0]). The adjusted risk of coronary heart disease mortality incident events among those with a 6 MWT < 290 m was not significant.

DISCUSSION: Performance on the 6 MWT is independently associated with all-cause mortality and is of prognostic utility in community-dwelling older adults.

1 aYazdanyar, Ali1 aAziz, Michael, M1 aEnright, Paul, L1 aEdmundowicz, Daniel1 aBoudreau, Robert1 aSutton-Tyrell, Kim1 aKuller, Lewis1 aNewman, Anne, B uhttps://chs-nhlbi.org/node/6341