02111nas a2200385 4500008004100000022001400041245009200055210006900147260001300216300001200229490000700241520101100248653000901259653002001268653003201288653003001320653001901350653001601369653002201385653001101407653001101418653003001429653000801459653000901467653001501476653003201491653003101523100001701554700001801571700002201589700001601611700001601627710004701643856003501690 2001 eng d a0895-435600aThe role of comorbidity in the assessment of intermittent claudication in older adults.0 arole of comorbidity in the assessment of intermittent claudicati c2001 Mar a294-3000 v543 a
The prevalence of intermittent claudication (IC) in older adults by questionnaire is less than 5% while the prevalence of peripheral arterial disease (PAD) by non-invasive testing is 2-4-fold higher. Comorbid conditions may result in under-reporting intermittent claudication (IC) as assessed by the Rose Questionnaire. We examined characteristics of those who report leg pain in relationship to other comorbid conditions and disability in 5888 participants of the Cardiovascular Health Study (CHS). Older adults with exertional leg pain, not meeting criteria for IC, had a higher prevalence of PAD on non-invasive testing with the ankle-arm index than those without pain, as well as a higher prevalence of arthritis. The pattern of responses suggested that pain for both conditions was reported together. The Rose Questionnaire for IC is specific for PAD, but a negative questionnaire does not indicate a lack of symptoms, rather the presence of PAD along with other conditions that can cause pain.
10aAged10aAngina Pectoris10aArterial Occlusive Diseases10aCerebrovascular Disorders10aCohort Studies10aComorbidity10aDiabetes Mellitus10aFemale10aHumans10aIntermittent Claudication10aLeg10aMale10aPrevalence10aSensitivity and Specificity10aSurveys and Questionnaires1 aNewman, A, B1 aNaydeck, B, L1 aSutton-Tyrrell, K1 aPolak, J, F1 aKuller, L H1 aCardiovascular Health Study Research Group uhttps://chs-nhlbi.org/node/638