02533nas a2200493 4500008004100000022001400041245009000055210006900145260001600214300001200230490000800242520121300250653002101463653001601484653000901500653002201509653001701531653001501548653001201563653001901575653001601594653002501610653002801635653002101663653001501684653001101699653001101710653002001721653000901741653003001750653001501780653001701795653002101812653001601833653003101849653001701880100001701897700001801914700002201932700001501954700001901969700001601988856003502004 2001 eng d a1524-453900aCoronary artery calcification in older adults to age 99: prevalence and risk factors.0 aCoronary artery calcification in older adults to age 99 prevalen c2001 Nov 27 a2679-840 v1043 a
BACKGROUND: Coronary artery calcification has been proposed as a noninvasive method to assess cardiovascular disease (CVD) risk. However, the prevalence and risk factors for coronary artery calcification in populations >65 years have not been well studied.
METHODS AND RESULTS: Electron beam tomography was performed to assess coronary artery calcium (CAC) in 614 older adults aged, on average, 80 years (range, 67 to 99 years); 367 (60%) were women, and 143 (23%) were black. Calcium scores ranged from 0 to 5459. Median scores were 622 for men and 205 for women. Scores increased by age and were lower in blacks than in whites. Nine percent of subjects (n=57) had no CAC, and 31% (n=190) had a score lower than 100. A history of CVD was associated with calcium score. Age, male sex, white race, CVD, triglyceride level, pack-years of smoking, and asthma, emphysema, or bronchitis (chronic obstructive pulmonary disease) were independently associated with CAC score in the fourth quartile.
CONCLUSIONS: A wide range of CAC scores was observed, suggesting adaptation with aging. CAC may have potential to predict CVD in older adults, but this remains to be determined.
10aAge Distribution10aAge Factors10aAged10aAged, 80 and over10aBlack People10aCalcinosis10aCalcium10aCohort Studies10aComorbidity10aCoronary Angiography10aCoronary Artery Disease10aCoronary Vessels10aDemography10aFemale10aHumans10aLogistic Models10aMale10aPredictive Value of Tests10aPrevalence10aRisk Factors10aSex Distribution10aSex Factors10aTomography, X-Ray Computed10aWhite People1 aNewman, A, B1 aNaydeck, B, L1 aSutton-Tyrrell, K1 aFeldman, A1 aEdmundowicz, D1 aKuller, L H uhttps://chs-nhlbi.org/node/667