03482nas a2200397   4500008004100000022001400041245016900055210006900224260001300293300001200306490000700318520230100325653000902626653001502635653002802650653001902678653001102697653001402708653001102722653000902733653001302742653001302755653001902768653001702787653003002804653001702834653001702851653002602868653003102894100002502925700002202950700002302972700002202995710003203017856003503049       2004                        eng d  a0277-953600aThe association of personal and neighborhood socioeconomic indicators with subclinical cardiovascular disease in an elderly cohort. The cardiovascular health study.0 aassociation of personal and neighborhood socioeconomic indicator  c2004 Nov  a2139-470 v593 a<p>There has been recent interest in determining whether neighborhood characteristics are related to the cardiovascular health of residents. However, there are no data regarding the relationship between neighborhood socioeconomic status (SES) and prevalence of subclinical cardiovascular disease (CVD) in the elderly. We related personal SES (education, income, and occupation type) and neighborhood socioeconomic characteristics (a block-group score summing six variables reflecting neighborhood income and wealth, education, and occupation) to the prevalence of subclinical CVD (asymptomatic peripheral vascular disease or carotid atherosclerosis, electrocardiogram or echocardiogram abnormalities, and/or positive responses to Rose Questionnaire claudication or angina pectoris) among 3545 persons aged 65 and over, without prevalent CVD, in the Cardiovascular Health Study. Sixty percent of participants had at least one indicator of subclinical disease. Compared to those without, those with subclinical disease had significantly lower education, income, and neighborhood scores and were more likely to have blue-collar jobs. After adjustment for age, gender, and race, those in the lowest SES groups had increased prevalence of subclinical disease compared with those in the highest SES groups (OR = 1.50; 95% CI 1.21, 1.86 for income; OR = 1.41; 95% CI 1.18, 1.69 for education; OR = 1.39; 95% CI 1.16, 1.67 for block-group score). Those reporting a blue-collar lifetime occupation had greater prevalence of subclinical disease relative to those reporting a white-collar occupation (OR = 1.29; 95% CI 1.02-1.59). After adjustment for behavioral and biomedical risk factors, all of these associations were reduced. Neighborhood score tended to remain inversely associated with subclinical disease after adjustment for personal socioeconomic indicators but associations were not statistically significant. Personal income and blue-collar occupation remained significantly associated with subclinical disease after simultaneous adjustment for neighborhood score and education. Personal and neighborhood socioeconomic indicators were associated with subclinical disease prevalence in this elderly cohort. These relationships were reduced after controlling for traditional CVD risk factors.</p>10aAged10aCalifornia10aCardiovascular Diseases10aCohort Studies10aFemale10aGeography10aHumans10aMale10aMaryland10aMedicare10aNorth Carolina10aPennsylvania10aResidence Characteristics10aRisk Factors10aSocial Class10aSocioeconomic Factors10aSurveys and Questionnaires1 aNordstrom, Cheryl, K1 aRoux, Ana, V Diez1 aJackson, Sharon, A1 aGardin, Julius, M1 aCardiovascular Health Study  uhttps://chs-nhlbi.org/node/799