03238nas a2200397 4500008004100000022001400041245013200055210006900187260001300256300001100269490000700280520209000287653001602377653000902393653001802402653001902420653002802439653002102467653002802488653002702516653002202543653001102565653001102576653000902587653001502596653002402611653001702635100002302652700002102675700002302696700002402719700002102743700002102764700002002785856003502805 2002 eng d a0002-861400aGlucose, blood pressure, and lipid control in older people with and without diabetes mellitus: the Cardiovascular Health Study.0 aGlucose blood pressure and lipid control in older people with an c2002 Mar a416-230 v503 a

OBJECTIVES: To determine the prevalence of cardiovascular risk-factor treatment and control in older adults with normal fasting glucose, impaired fasting glucose, and diabetes mellitus and whether those with diabetes mellitus had better risk factor control than older adults with normal fasting glucose.

DESIGN: Secondary analysis of data from population-based, prospective cohort study of risk factors for cardio-vascular and cerebrovascular disease in older people (Cardiovascular Health Study).

SETTING: Community-based.

PARTICIPANTS: Community-dwelling adults aged 65 and older.

MEASUREMENTS: Fasting plasma glucose, serum cholesterol and its subfractions, systolic and diastolic blood pressures, and body mass index.

RESULTS: There were 579 (18%) cohort members with diabetes mellitus (77% receiving antidiabetic medication, 23% with fasting glucose > or =126 mg/dL and no treatment), 213 (6%) with impaired fasting glucose, and 2,582 (77%)with normal fasting glucose. Of diabetic participants, 12% had recommended fasting glucose levels of less than 110 mg/dL. Of participants with hypertension, a larger proportion of diabetic participants than nondiabetic participants (89% versus 75%, P < .01) was treated with antihypertensive agents, but a smaller proportion of diabetic participants had recommended blood pressure levels of 129/85 mmHg or lower than nondiabetic participants had recommended blood pressure levels of 139/89 mmHg or lower (27% vs 48%, P < .01). Diabetic dyslipidemic participants were treated less often with lipid-lowering therapy (26% versus 55%, P < .01) and achieved recommended low-density lipoprotein goals less often (8%versus 54%, P < .01) than nondiabetic dyslipidemic participants.

CONCLUSIONS: Overall, treatment and control of cardiovascular risk factors were suboptimal in this older population, especially among those with diabetes mellitus. Optimizing risk-factor control can improve health outcomes in older adults with and without diabetes mellitus.

10aAge Factors10aAged10aBlood Glucose10aBlood Pressure10aCardiovascular Diseases10aCholesterol, LDL10aCross-Sectional Studies10aDiabetes Complications10aDiabetes Mellitus10aFemale10aHumans10aMale10aPrevalence10aProspective Studies10aRisk Factors1 aSmith, Nicholas, L1 aSavage, Peter, J1 aHeckbert, Susan, R1 aBarzilay, Joshua, I1 aBittner, Vera, A1 aKuller, Lewis, H1 aPsaty, Bruce, M uhttps://chs-nhlbi.org/node/685