03750nas a2200481 4500008004100000022001400041245014400055210006900199260001300268300001000281490000700291520238900298653001002687653000902697653002202706653001002728653001202738653002002750653002102770653002402791653002102815653002302836653001102859653001102870653000902881653001602890653002302906653002002929653001602949653002602965653001702991653001703008100002003025700002503045700001703070700001803087700002303105700001903128700001803147700001703165710005103182856003503233 2002 eng d a0161-810500aShort-term variability of respiration and sleep during unattended nonlaboratory polysomnography--the Sleep Heart Health Study. [corrected].0 aShortterm variability of respiration and sleep during unattended c2002 Dec a843-90 v253 a

STUDY OBJECTIVES: To determine the short-term variability of indices of disturbed respiration and sleep during 2 nights of unattended nonlaboratory polysomnography conducted several months apart.

DESIGN: Participants were randomly selected using a block design with stratification on preliminary estimates of 2 criteria: respiratory disturbance index [RDI3% (apnea or hypopnea events associated with > or = 3% O2 desaturation): < 15/hour total sleep time, > or = 15/hour total sleep time] and sleep efficiency (SEff: < 85% and > or = 85%). The RDI and sleep data from initial and repeated polysomnography were compared.

SETTING: NA.

PARTICIPANTS: A subset of 99 participants in the Sleep Heart Health Study who agreed to have a repeat polysomnogram within 4 months of their original study.

INTERVENTIONS: NA.

MEASUREMENTS AND RESULTS: Acceptable repeat polysomnograms were obtained in 91 subjects (mean study interval: 77 +/- 18 [sd] days; range: 31-112 days). There was no significant bias in RDI between study nights using several different RDI definitions including RDI3% and RDI4% (apnea or hypopnea events associated with > or = 4% O2 desaturation). Variability between studies estimated using intraclass correlations (ICC) ranged from 0.77 to 0.81. For subjects with a RDI3% < 15, variability increased as a function of increasing RDI, but for those with a RDI3% > or = 15, variability was constant. Body mass index, SEff, gender, or age did not directly predict RDI variability. Using RDI4% cutpoints of < or = 5, < or = 10 and < or = 15 events per hour of sleep demonstrated that 79.1%, 85.7%, and 87.9% of subjects, respectively, had the same classification of SDB status on both nights of study. There also was no significant bias in sleep staging, sleep efficiency, or arousal index between studies. However, variability was greater with ICC values ranging from 0.37 (% time in REM) to 0.76 (arousal index).

CONCLUSION: In the Sleep Heart Health Study, accurate estimates of the severity of sleep-disordered breathing and the quality of sleep were obtained from a single night of unattended nonlaboratory polysomnography. These findings may be applicable to other large epidemiologic studies provided that similar recording techniques and quality-assurance procedures are followed.

10aAdult10aAged10aAged, 80 and over10aApnea10aArousal10aBody Mass Index10aCircadian Rhythm10aElectrocardiography10aElectromyography10aElectrooculography10aFemale10aHumans10aMale10aMiddle Aged10aOxygen Consumption10aPolysomnography10aRespiration10aSleep Apnea Syndromes10aSleep Stages10aTime Factors1 aQuan, Stuart, F1 aGriswold, Michael, E1 aIber, Conrad1 aNieto, Javier1 aRapoport, David, M1 aRedline, Susan1 aSanders, Mark1 aYoung, Terry1 aSleep Heart Health Study (SHHS) Research Group uhttps://chs-nhlbi.org/node/71402691nas a2200325 4500008004100000022001400041245010300055210006900158260001300227300001200240490000700252520180600259653000902065653001202074653001902086653001102105653001102116653000902127653001602136653002002152653002002172653002902192653001202221653001202233100001902245700002302264700002202287700002002309856003602329 2008 eng d a0161-810500aEffect of sleep disordered breathing on the sleep of bed partners in the Sleep Heart Health Study.0 aEffect of sleep disordered breathing on the sleep of bed partner c2008 Oct a1449-560 v313 a

OBJECTIVE: To study the sleep quality of bed partners of persons with sleep disordered breathing in a non-clinical population based sample in a home environment.

DESIGN: Cross-sectional study in a community sample.

METHODS: 110 pairs of subjects living in the same household from the Tucson, Minnesota, and Pittsburgh sites of the Sleep Heart Health Study (SHHS) were included if both partners had an in-home, unattended polysomnogram (PSG) performed as a part of SHHS exam cycle 2. Sleep disordered breathing (SDB) was considered present if the respiratory disturbance index (RDI) was > or =10 events/h and no SDB if RDI was <5 events/h. Pairs were classified according to their SDB status and assigned to one of 3 groups: 1) NoSDB-NoSDB (n = 46), 2) NoSDB-SDB (n = 42), and 3) SDB-SDB (n = 22).

RESULTS: There were no differences between the NoSDB-NoSDB and the SDB-SDB partners in their demographic, PSG, or quality of life variables. However, within the NoSDB-SDB group, NoSDB in comparison to their SDB partners weighed less (mean BMI: 26 vs. 29 kg/m2, P < 0.0003), had decreased stage 2% (55 vs. 64, P < 0.0001), increased stage 3 and 4% (21 vs. 11, P <0.0005) and a lower arousal index (13.8 vs. 20 events/h, P < 0.0001). When comparing the NoSDB subjects from the NoSDB-SDB group to subjects in the NoSDB-NoSDB group and to subjects in the SDB-SDB group, significant differences were seen for RDI and BMI but not for any other parameter.

CONCLUSION: In a non-clinical population based sample, the sleep quality of bed partners of SDB subjects without SDB is better than their SDB bed partner. However, their sleep quality was not different in comparison to the sleep of those without SDB who also had a bed partner without SDB.

10aAged10aArousal10aCohort Studies10aFemale10aHumans10aMale10aMiddle Aged10aPolysomnography10aQuality of Life10aSleep Apnea, Obstructive10aSnoring10aSpouses1 aSharief, Imran1 aSilva, Graciela, E1 aGoodwin, James, L1 aQuan, Stuart, F uhttps://chs-nhlbi.org/node/1059