02516nas a2200241 4500008004100000022001400041245009700055210006900152260001600221520176900237100002302006700002502029700002202054700002102076700002202097700001702119700001602136700002202152700002202174700001902196700002302215856003602238 2020 eng d a1532-541500aAccelerometer-Measured Sedentary Patterns are Associated with Incident Falls in Older Women.0 aAccelerometerMeasured Sedentary Patterns are Associated with Inc c2020 Nov 303 a

BACKGROUND/OBJECTIVE: Falls cause significant problems for older adults. Sedentary time is associated with lower physical function and could increase the risk for falls.

DESIGN: Prospective study.

SETTING: Sites across the United States.

PARTICIPANTS: Older women (N = 5,545, mean age 79 years) from the Women' Health Initiative Objective Physical Activity and Cardiovascular Health study.

MEASUREMENTS: Accelerometers worn at the hip for up to 1 week collected measures of daily sedentary time and the mean sedentary bout duration, a commonly used metric for sedentary accumulation patterns. For up to 13 months after accelerometer wear, women reported daily whether they had fallen on monthly calendars.

RESULTS: In fully adjusted models, the incident rate ratios (95% confidence interval) for quartiles 1 (lowest), 2, 3, and 4 of sedentary time respectively were 1.0 (ref.), 1.07 (0.93-1.24), 1.07 (0.91-1.25), and 1.14 (0.96-1.35; P-trend = .65) and for mean sedentary bout duration was 1.0 (ref.), 1.05 (0.92-1.21), 1.02 (0.88-1.17), and 1.17 (1.01-1.37; P-trend = .01), respectively. Women with a history of two or more falls had stronger associations between sedentary time and falls incidence compared with women with a history of no or one fall (P for interaction = .046).

CONCLUSIONS: Older women in the highest quartile of mean sedentary bout duration had a significantly increased risk of falling. Women with a history of frequent falling may be at higher risk for falling if they have high sedentary time. Interventions testing whether shortening total sedentary time and/or sedentary bouts lowers fall risk are needed to confirm these observational findings.

1 aRosenberg, Dori, E1 aRillamas-Sun, Eileen1 aBellettiere, John1 aLaMonte, Michael1 aBuchner, David, M1 aDi, Chongzhi1 aHunt, Julie1 aMarshall, Stephen1 aStefanick, Marcia1 aZhang, Yuzheng1 aLaCroix, Andrea, Z uhttps://chs-nhlbi.org/node/8619