TY - JOUR T1 - Sleepiness in patients with moderate to severe sleep-disordered breathing. JF - Sleep Y1 - 2005 A1 - Kapur, Vishesh K A1 - Baldwin, Carol M A1 - Resnick, Helaine E A1 - Gottlieb, Daniel J A1 - Nieto, F Javier KW - Aged KW - Body Mass Index KW - Cohort Studies KW - Cross-Sectional Studies KW - Disorders of Excessive Somnolence KW - Female KW - Humans KW - Male KW - Middle Aged KW - Oxygen KW - Polysomnography KW - Prevalence KW - Risk Factors KW - Severity of Illness Index KW - Sleep Apnea Syndromes KW - Sleep Arousal Disorders KW - Sleep Stages KW - Surveys and Questionnaires AB -

BACKGROUND: Population-based studies suggest that complaints of sleepiness are absent in many individuals with sleep-disordered breathing. We investigated the prevalence of sleepiness as well as factors associated with sleepiness in individuals with moderate to severe sleep-disordered breathing (apnea-hypopnea index > or = 15).

DESIGN: Cross-sectional study.

SETTING: The Sleep Heart Health Study.

PARTICIPANTS: Sleep Heart Health Study participants (N = 6440).

MEASUREMENTS AND RESULTS: Sleepiness was defined as an Epworth Sleepiness Scale score >10 or a report of at least frequently feeling unrested or sleepy. Forty-six percent of participants with moderate to severe sleep-disordered breathing (n = 1149) reported sleepiness. Characteristics associated with sleepiness after adjustment for confounders included presence of respiratory disease, shorter self-reported weekday and weekend sleep, sleep durations, complaints of insufficient sleep, complaints of sleep maintenance insomnia, early morning awakening, habitual snoring, and complaints of awakening with leg cramps or leg jerks. Some respiratory polysomnography measures were associated with sleepiness, but sleep-stage percentages and measures of sleep disruption were not.

CONCLUSIONS: In this community-based cohort, subjective sleepiness is absent in many individuals with significant sleep-disordered breathing. Comorbid conditions, including respiratory disease, sleep restriction, insomnia, and nocturnal leg complaints, are important risk factors for sleepiness in individuals with moderate to severe sleep-disordered breathing.

VL - 28 IS - 4 U1 - https://www.ncbi.nlm.nih.gov/pubmed/16171292?dopt=Abstract ER -