Lumley T, Kronmal RA, Cushman M, Manolio TA, Goldstein S. A stroke prediction score in the elderly: validation and Web-based application. J Clin Epidemiol. 2002  ;55(2):129-36.

Psaty BM, Manolio TA, Smith NL, Heckbert SR, Gottdiener JS, Burke GL, Weissfeld J, Enright P, Lumley T, Powe N, et al. Time trends in high blood pressure control and the use of antihypertensive medications in older adults: the Cardiovascular Health Study. Arch Intern Med. 2002  ;162(20):2325-32.

Smith NL, Psaty BM, Rutan GH, Lumley T, Yanez D, Chaves PHM, Kronmal RA. The association between time since last meal and blood pressure in older adults: the cardiovascular health study. J Am Geriatr Soc. 2003  ;51(6):824-8.

Heckbert SR, Hindorff LA, Edwards KL, Psaty BM, Lumley T, Siscovick DS, Tang Z, J Durda P, Kronmal RA, Tracy RP. Beta2-adrenergic receptor polymorphisms and risk of incident cardiovascular events in the elderly. Circulation. 2003  ;107(15):2021-4.

Psaty BM, Anderson M, Kronmal RA, Tracy RP, Orchard T, Fried LP, Lumley T, Robbins J, Burke G, Newman AB, et al. The association between lipid levels and the risks of incident myocardial infarction, stroke, and total mortality: The Cardiovascular Health Study. J Am Geriatr Soc. 2004  ;52(10):1639-47.

Schellenbaum GD, Rea TD, Heckbert SR, Smith NL, Lumley T, Roger VL, Kitzman DW, Taylor HA, Levy D, Psaty BM. Survival associated with two sets of diagnostic criteria for congestive heart failure. Am J Epidemiol. 2004  ;160(7):628-35.

Smith NL, Chan JD, Rea TD, Wiggins KL, Gottdiener JS, Lumley T, Psaty BM. Time trends in the use of beta-blockers and other pharmacotherapies in older adults with congestive heart failure. Am Heart J. 2004  ;148(4):710-7.

Chan JD, Rea TD, Smith NL, Siscovick D, Heckbert SR, Lumley T, Chaves P, Furberg CD, Kuller L, Psaty BM. Association of beta-blocker use with mortality among patients with congestive heart failure in the Cardiovascular Health Study (CHS). Am Heart J. 2005  ;150(3):464-70.

Hindorff LA, Heckbert SR, Psaty BM, Lumley T, Siscovick DS, Herrington DM, Edwards KL, Tracy RP. beta(2)-Adrenergic receptor polymorphisms and determinants of cardiovascular risk: the Cardiovascular Health Study. Am J Hypertens. 2005  ;18(3):392-7.

Reiner AP, Diehr P, Browner WS, Humphries SE, Jenny NS, Cushman M, Tracy RP, Walston J, Lumley T, Newman AB, et al. Common promoter polymorphisms of inflammation and thrombosis genes and longevity in older adults: the cardiovascular health study. Atherosclerosis. 2005  ;181(1):175-83.

Schellenbaum GD, Smith NL, Heckbert SR, Lumley T, Rea TD, Furberg CD, Lyles MF, Psaty BM. Weight loss, muscle strength, and angiotensin-converting enzyme inhibitors in older adults with congestive heart failure or hypertension. J Am Geriatr Soc. 2005  ;53(11):1996-2000.

Mukamal KJ, Lumley T, Luepker RV, Lapin P, Mittleman MA, A McBean M, Crum RM, Siscovick DS. Alcohol consumption in older adults and Medicare costs. Health Care Financ Rev. 2006  ;27(3):49-61.

Schellenbaum GD, Heckbert SR, Smith NL, Rea TD, Lumley T, Kitzman DW, Roger VL, Taylor HA, Psaty BM. Congestive heart failure incidence and prognosis: case identification using central adjudication versus hospital discharge diagnoses. Ann Epidemiol. 2006  ;16(2):115-22.

Smith NL, Barzilay JI, Kronmal R, Lumley T, Enquobahrie D, Psaty BM. New-onset diabetes and risk of all-cause and cardiovascular mortality: the Cardiovascular Health Study. Diabetes Care. 2006  ;29(9):2012-7.

Cai T, Pepe MSullivan, Zheng Y, Lumley T, Jenny NSwords. The sensitivity and specificity of markers for event times. Biostatistics. 2006  ;7(2):182-97.

Shiffman D, O'Meara ES, Bare LA, Rowland CM, Louie JZ, Arellano AR, Lumley T, Rice K, Iakoubova O, Luke MM, et al. Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study. Arterioscler Thromb Vasc Biol. 2008  ;28(1):173-9.

van Stralen KJ, Doggen CJM, Lumley T, Cushman M, Folsom AR, Psaty BM, Siscovick D, Rosendaal FR, Heckbert SR. The relationship between exercise and risk of venous thrombosis in elderly people. J Am Geriatr Soc. 2008  ;56(3):517-22.

Dehghan A, Yang Q, Peters A, Basu S, Bis JC, Rudnicka AR, Kavousi M, Chen M-H, Baumert J, Lowe GDO, et al. Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts. Circ Cardiovasc Genet. 2009  ;2(2):125-33.

Newton-Cheh C, Eijgelsheim M, Rice KM, de Bakker PIW, Yin X, Estrada K, Bis JC, Marciante K, Rivadeneira F, Noseworthy PA, et al. Common variants at ten loci influence QT interval duration in the QTGEN Study. Nat Genet. 2009  ;41(4):399-406.

Luke MM, O'Meara ES, Rowland CM, Shiffman D, Bare LA, Arellano AR, Longstreth WT, Lumley T, Rice K, Tracy RP, et al. Gene variants associated with ischemic stroke: the cardiovascular health study. Stroke. 2009  ;40(2):363-8.

Vasan RS, Glazer NL, Felix JF, Lieb W, Wild PS, Felix SB, Watzinger N, Larson MG, Smith NL, Dehghan A, et al. Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. JAMA. 2009  ;302(2):168-78.

Ikram AM, Seshadri S, Bis JC, Fornage M, DeStefano AL, Aulchenko YS, Debette S, Lumley T, Folsom AR, van den Herik EG, et al. Genomewide association studies of stroke. N Engl J Med. 2009  ;360(17):1718-28.

Levy D, Ehret GB, Rice K, Verwoert GC, Launer LJ, Dehghan A, Glazer NL, Morrison AC, Johnson AD, Aspelund T, et al. Genome-wide association study of blood pressure and hypertension. Nat Genet. 2009  ;41(6):677-87.

Köttgen A, Glazer NL, Dehghan A, Hwang S-J, Katz R, Li M, Yang Q, Gudnason V, Launer LJ, Harris TB, et al. Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet. 2009  ;41(6):712-7.

Ganesh SK, Zakai NA, van Rooij FJA, Soranzo N, Smith AV, Nalls MA, Chen M-H, Köttgen A, Glazer NL, Dehghan A, et al. Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet. 2009  ;41(11):1191-8.

Newman AB, Sachs MC, Arnold AM, Fried LP, Kronmal R, Cushman M, Psaty BM, Harris TB, Robbins JA, Burke GL, et al. Total and cause-specific mortality in the cardiovascular health study. J Gerontol A Biol Sci Med Sci. 2009  ;64(12):1251-61.

Benjamin EJ, Rice KM, Arking DE, Pfeufer A, van Noord C, Smith AV, Schnabel RB, Bis JC, Boerwinkle E, Sinner MF, et al. Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nat Genet. 2009  ;41(8):879-81.

Smith NL, Felix JF, Morrison AC, Demissie S, Glazer NL, Loehr LR, Cupples AL, Dehghan A, Lumley T, Rosamond WD, et al. Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. Circ Cardiovasc Genet. 2010  ;3(3):256-66.

M Ikram K, Sim X, Xueling S, Jensen RA, Cotch MFrances, Hewitt AW, Ikram AM, Wang JJin, Klein R, Klein BEK, et al. Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. PLoS Genet. 2010  ;6(10):e1001184.

Seshadri S, Fitzpatrick AL, Ikram AM, DeStefano AL, Gudnason V, Boada M, Bis JC, Smith AV, Carassquillo MM, Lambert JCharles, et al. Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA. 2010  ;303(18):1832-40.

Debette S, Bis JC, Fornage M, Schmidt H, Ikram AM, Sigurdsson S, Heiss G, Struchalin M, Smith AV, van der Lugt A, et al. Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium. Stroke. 2010  ;41(2):210-7.

Morrison AC, Felix JF, Cupples AL, Glazer NL, Loehr LR, Dehghan A, Demissie S, Bis JC, Rosamond WD, Aulchenko YS, et al. Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium. Circ Cardiovasc Genet. 2010  ;3(3):248-55.

Hancock DB, Eijgelsheim M, Wilk JB, Gharib SA, Loehr LR, Marciante KD, Franceschini N, van Durme YMTA, Chen T-H, R Barr G, et al. Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nat Genet. 2010  ;42(1):45-52.

Newman AB, Walter S, Lunetta KL, Garcia ME, P Slagboom E, Christensen K, Arnold AM, Aspelund T, Aulchenko YS, Benjamin EJ, et al. A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. J Gerontol A Biol Sci Med Sci. 2010  ;65(5):478-87.

Yang Q, Köttgen A, Dehghan A, Smith AV, Glazer NL, Chen M-H, Chasman DI, Aspelund T, Eiriksdottir G, Harris TB, et al. Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. Circ Cardiovasc Genet. 2010  ;3(6):523-30.

Köttgen A, Pattaro C, Böger CA, Fuchsberger C, Olden M, Glazer NL, Parsa A, Gao X, Yang Q, Smith AV, et al. New loci associated with kidney function and chronic kidney disease. Nat Genet. 2010  ;42(5):376-84.

Smith NL, Chen M-H, Dehghan A, Strachan DP, Basu S, Soranzo N, Hayward C, Rudan I, Sabater-Lleal M, Bis JC, et al. Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium. Circulation. 2010  ;121(12):1382-92.

Marciante KD, Durda JP, Heckbert SR, Lumley T, Rice K, McKnight B, Totah RA, Tamraz B, Kroetz DL, Fukushima H, et al. Cerivastatin, genetic variants, and the risk of rhabdomyolysis. Pharmacogenet Genomics. 2011  ;21(5):280-8.

Böger CA, Chen M-H, Tin A, Olden M, Köttgen A, de Boer IH, Fuchsberger C, O'Seaghdha CM, Pattaro C, Teumer A, et al. CUBN is a gene locus for albuminuria. J Am Soc Nephrol. 2011  ;22(3):555-70.

Lemaitre RN, Tanaka T, Tang W, Manichaikul A, Foy M, Kabagambe EK, Nettleton JA, King IB, Weng L-C, Bhattacharya S, et al. Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. PLoS Genet. 2011  ;7(7):e1002193.

Smith NL, Huffman JE, Strachan DP, Huang J, Dehghan A, Trompet S, Lopez LM, Shin S-Y, Baumert J, Vitart V, et al. Genetic predictors of fibrin D-dimer levels in healthy adults. Circulation. 2011  ;123(17):1864-72.

Artigas MSoler, Loth DW, Wain LV, Gharib SA, Obeidat M'en, Tang W, Zhai G, Zhao JH, Smith AVernon, Huffman JE, et al. Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet. 2011  ;43(11):1082-90.

Fornage M, Debette S, Bis JC, Schmidt H, Ikram AM, Dufouil C, Sigurdsson S, Lumley T, DeStefano AL, Fazekas F, et al. Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium. Ann Neurol. 2011  ;69(6):928-39.

Elkind MSV, Carty CL, O'Meara ES, Lumley T, Lefkowitz D, Kronmal RA, Longstreth WT. Hospitalization for infection and risk of acute ischemic stroke: the Cardiovascular Health Study. Stroke. 2011  ;42(7):1851-6.

Gieger C, Radhakrishnan A, Cvejic A, Tang W, Porcu E, Pistis G, Serbanovic-Canic J, Elling U, Goodall AH, Labrune Y, et al. New gene functions in megakaryopoiesis and platelet formation. Nature. 2011  ;480(7376):201-8.

Wilk JB, Shrine NRG, Loehr LR, Zhao JH, Manichaikul A, Lopez LM, Smith AVernon, Heckbert SR, Smolonska J, Tang W, et al. Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. Am J Respir Crit Care Med. 2012  ;186(7):622-32.

Hancock DB, Artigas MSoler, Gharib SA, Henry A, Manichaikul A, Ramasamy A, Loth DW, Imboden M, Koch B, McArdle WL, et al. Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function. PLoS Genet. 2012  ;8(12):e1003098.

Glazer NL, Macy EM, Lumley T, Smith NL, Reiner AP, Psaty BM, King GL, Tracy RP, Siscovick DS. Transforming growth factor beta-1 and incidence of heart failure in older adults: the Cardiovascular Health Study. Cytokine. 2012  ;60(2):341-5.

Sim X, Jensen RA, M Ikram K, Cotch MFrances, Li X, Macgregor S, Xie J, Smith AVernon, Boerwinkle E, Mitchell P, et al. Genetic loci for retinal arteriolar microcirculation. PLoS One. 2013  ;8(6):e65804.

Tang W, Teichert M, Chasman DI, Heit JA, Morange P-E, Li G, Pankratz N, Leebeek FW, Paré G, de Andrade M, et al. A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. Genet Epidemiol. 2013  ;37(5):512-521.

Jensen RA, Sim X, Li X, Cotch MFrances, M Ikram K, Holliday EG, Eiriksdottir G, Harris TB, Jonasson F, Klein BEK, et al. Genome-wide association study of retinopathy in individuals without diabetes. PLoS One. 2013  ;8(2):e54232.

Holliday EG, Smith AV, Cornes BK, Buitendijk GHS, Jensen RA, Sim X, Aspelund T, Aung T, Baird PN, Boerwinkle E, et al. Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. PLoS One. 2013  ;8(1):e53830.

Sabater-Lleal M, Huang J, Chasman D, Naitza S, Dehghan A, Johnson AD, Teumer A, Reiner AP, Folkersen L, Basu S, et al. Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation. 2013  ;128(12):1310-24.

London SJ, Gao W, Gharib SA, Hancock DB, Wilk JB, House JS, Gibbs RA, Muzny DM, Lumley T, Franceschini N, et al. ADAM19 and HTR4 variants and pulmonary function: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circ Cardiovasc Genet. 2014  ;7(3):350-8.

Bis JC, DeStefano A, Liu X, Brody JA, Choi SHoan, Verhaaren BFJ, Debette S, Ikram AM, Shahar E, Butler KR, et al. Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium. PLoS One. 2014  ;9(6):e99798.

Bihlmeyer NA, Brody JA, Smith AVernon, Lunetta KL, Nalls M, Smith JA, Tanaka T, Davies G, Yu L, Mirza SSaeed, et al. Genetic diversity is a predictor of mortality in humans. BMC Genet. 2014  ;15:159.

Loth DW, Artigas MSoler, Gharib SA, Wain LV, Franceschini N, Koch B, Pottinger TD, Smith AVernon, Duan Q, Oldmeadow C, et al. Genome-wide association analysis identifies six new loci associated with forced vital capacity. Nat Genet. 2014  ;46(7):669-77.

Tang W, Kowgier M, Loth DW, Artigas MSoler, Joubert BR, Hodge E, Gharib SA, Smith AV, Ruczinski I, Gudnason V, et al. Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function. PLoS One. 2014  ;9(7):e100776.

Baumert J, Huang J, McKnight B, Sabater-Lleal M, Steri M, Chu AY, Trompet S, Lopez LM, Fornage M, Teumer A, et al. No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects. PLoS One. 2014  ;9(12):e111156.

Postmus I, Trompet S, Deshmukh HA, Barnes MR, Li X, Warren HR, Chasman DI, Zhou K, Arsenault BJ, Donnelly LA, et al. Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins. Nat Commun. 2014  ;5:5068.

Ibrahim-Verbaas CA, Fornage M, Bis JC, Choi SHoan, Psaty BM, Meigs JB, Rao M, Nalls M, Fontes JD, O'Donnell CJ, et al. Predicting stroke through genetic risk functions: the CHARGE Risk Score Project. Stroke. 2014  ;45(2):403-12.

Morrison AC, Bis JC, Hwang S-J, Ehret GB, Lumley T, Rice K, Muzny D, Gibbs RA, Boerwinkle E, Psaty BM, et al. Sequence analysis of six blood pressure candidate regions in 4,178 individuals: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study. PLoS One. 2014  ;9(10):e109155.

Magnani JW, Brody JA, Prins BP, Arking DE, Lin H, Yin X, Liu C-T, Morrison AC, Zhang F, Spector TD, et al. Sequencing of SCN5A identifies rare and common variants associated with cardiac conduction: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. Circ Cardiovasc Genet. 2014  ;7(3):365-73.

Lin H, Wang M, Brody JA, Bis JC, Dupuis J, Lumley T, McKnight B, Rice KM, Sitlani CM, Reid JG, et al. Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circ Cardiovasc Genet. 2014  ;7(3):335-43.

Lange LA, Hu Y, Zhang H, Xue C, Schmidt EM, Tang Z-Z, Bizon C, Lange EM, Smith JD, Turner EH, et al. Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. Am J Hum Genet. 2014  ;94(2):233-45.

Smith CE, Follis JL, Nettleton JA, Foy M, H Y Wu J, Ma Y, Tanaka T, Manichakul AW, Wu H, Chu AY, et al. Dietary fatty acids modulate associations between genetic variants and circulating fatty acids in plasma and erythrocyte membranes: Meta-analysis of nine studies in the CHARGE consortium. Mol Nutr Food Res. 2015  ;59(7):1373-83.

Bis JC, Sitlani C, Irvin R, Avery CL, Smith AVernon, Sun F, Evans DS, Musani SK, Li X, Trompet S, et al. Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium. PLoS One. 2015  ;10(10):e0140496.

Sitlani CM, Rice KM, Lumley T, McKnight B, Cupples AL, Avery CL, Noordam R, Stricker BHC, Whitsel EA, Psaty BM. Generalized estimating equations for genome-wide association studies using longitudinal phenotype data. Stat Med. 2015  ;34(1):118-30.

B?zková P. Time to diagnosis: accounting for differential follow-up times in cohort studies. Lumley T. Communications in Statistics-Simulation and Computation. 2015  ;44(1).

Hofer E, Cavalieri M, Bis JC, DeCarli C, Fornage M, Sigurdsson S, Srikanth V, Trompet S, Verhaaren BFJ, Wolf C, et al. White Matter Lesion Progression: Genome-Wide Search for Genetic Influences. Stroke. 2015  ;46(11):3048-57.

Dehghan A, Bis JC, White CC, Smith AVernon, Morrison AC, Cupples AL, Trompet S, Chasman DI, Lumley T, Völker U, et al. Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium. PLoS One. 2016  ;11(3):e0144997.

Postmus I, Warren HR, Trompet S, Arsenault BJ, Avery CL, Bis JC, Chasman DI, de Keyser CE, Deshmukh HA, Evans DS, et al. Meta-analysis of genome-wide association studies of HDL cholesterol response to statins. J Med Genet. 2016  ;53(12):835-845.

Joshi PK, Pirastu N, Kentistou KA, Fischer K, Hofer E, Schraut KE, Clark DW, Nutile T, Barnes CLK, Timmers PRHJ, et al. Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity. Nat Commun. 2017  ;8(1):910.

Macri V, Brody JA, Arking DE, Hucker WJ, Yin X, Lin H, Mills RW, Sinner MF, Lubitz SA, Liu C-T, et al. Common Coding Variants in  Are Associated With the Nav1.8 Late Current and Cardiac Conduction. Circ Genom Precis Med. 2018  ;11(5):e001663.

Ashar FN, Mitchell RN, Albert CM, Newton-Cheh C, Brody JA, Müller-Nurasyid M, Moes A, Meitinger T, Mak A, Huikuri H, et al. A comprehensive evaluation of the genetic architecture of sudden cardiac arrest. Eur Heart J. 2018  .

Lumley T, Brody J, Peloso G, Morrison A, Rice K. FastSKAT: Sequence kernel association tests for very large sets of markers. Genet Epidemiol. 2018  ;42(6):516-527.

Clark DW, Okada Y, Moore KHS, Mason D, Pirastu N, Gandin I, Mattsson H, Barnes CLK, Lin K, Zhao JH, et al. Associations of autozygosity with a broad range of human phenotypes. Nat Commun. 2019  ;10(1):4957.

Sitlani CM, Lumley T, McKnight B, Rice KM, Olson NC, Doyle MF, Huber SA, Tracy RP, Psaty BM, Delaney JAC. Incorporating sampling weights into robust estimation of Cox proportional hazards regression model, with illustration in the Multi-Ethnic Study of Atherosclerosis. BMC Med Res Methodol. 2020  ;20(1):62.