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5

van der Harst P, van Setten J, Verweij N, Vogler G, Franke L, Maurano MT, Wang X, Leach IMateo, Eijgelsheim M, Sotoodehnia N, et al. 52 Genetic Loci Influencing Myocardial Mass. J Am Coll Cardiol. 2016 ;68(13):1435-48.

A

Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU, Allen HLango, Lindgren CM, Luan J'an, Mägi R, et al. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet. 2010 ;42(11):937-48.

Chauhan G, Adams HHH, Bis JC, Weinstein G, Yu L, Töglhofer AMaria, Smith AVernon, van der Lee SJ, Gottesman RF, Thomson R, et al. Association of Alzheimer's disease GWAS loci with MRI markers of brain aging. Neurobiol Aging. 2015 ;36(4):1765.e7-16.

Johnson AD, Newton-Cheh C, Chasman DI, Ehret GB, Johnson T, Rose L, Rice K, Verwoert GC, Launer LJ, Gudnason V, et al. Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals. Hypertension. 2011 ;57(5):903-10.

Bressler J, Davies G, Smith AV, Saba Y, Bis JC, Jian X, Hayward C, Yanek L, Smith JA, Mirza SS, et al. Association of low-frequency and rare coding variants with information processing speed. Transl Psychiatry. 2021 ;11(1):613.

Peloso GM, Auer PL, Bis JC, Voorman A, Morrison AC, Stitziel NO, Brody JA, Khetarpal SA, Crosby JR, Fornage M, et al. Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. Am J Hum Genet. 2014 ;94(2):223-32.

Mishra A, Chauhan G, Violleau M-H, Vojinovic D, Jian X, Bis JC, Li S, Saba Y, Grenier-Boley B, Yang Q, et al. Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects. Brain. 2019 .

Clark DW, Okada Y, Moore KHS, Mason D, Pirastu N, Gandin I, Mattsson H, Barnes CLK, Lin K, Zhao JH, et al. Associations of autozygosity with a broad range of human phenotypes. Nat Commun. 2019 ;10(1):4957.

Frenzel S, Bis JC, Gudmundsson EF, O'Donnell A, Simino J, Yaqub A, Bartz TM, Brusselle GGO, Bülow R, DeCarli CS, et al. Associations of Pulmonary Function with MRI Brain Volumes: A Coordinated Multi-Study Analysis. J Alzheimers Dis. 2022 .

B

Grove ML, Yu B, Cochran BJ, Haritunians T, Bis JC, Taylor KD, Hansen M, Borecki IB, Cupples AL, Fornage M, et al. Best practices and joint calling of the HumanExome BeadChip: the CHARGE Consortium. PLoS One. 2013 ;8(7):e68095.

Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, Pirruccello JP, Ripatti S, Chasman DI, Willer CJ, et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 2010 ;466(7307):707-13.

Sinner MF, Stepas KA, Moser CB, Krijthe BP, Aspelund T, Sotoodehnia N, Fontes JD, A Janssens CJW, Kronmal RA, Magnani JW, et al. B-type natriuretic peptide and C-reactive protein in the prediction of atrial fibrillation risk: the CHARGE-AF Consortium of community-based cohort studies. Europace. 2014 ;16(10):1426-33.

C

van Leeuwen EM, Smouter FAS, Kam-Thong T, Karbalai N, Smith AV, Harris TB, Launer LJ, Sitlani CM, Li G, Brody JA, et al. The challenges of genome-wide interaction studies: lessons to learn from the analysis of HDL blood levels. PLoS One. 2014 ;9(10):e109290.

Lin H, van Setten J, Smith AV, Bihlmeyer NA, Warren HR, Brody JA, Radmanesh F, Hall L, Grarup N, Müller-Nurasyid M, et al. Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval. Circ Genom Precis Med. 2018 ;11(5):e002037.

Ellinor PT, Lunetta KL, Glazer NL, Pfeufer A, Alonso A, Chung MK, Sinner MF, de Bakker PIW, Mueller M, Lubitz SA, et al. Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet. 2010 ;42(3):240-4.

Parsa A, Fuchsberger C, Köttgen A, O'Seaghdha CM, Pattaro C, de Andrade M, Chasman DI, Teumer A, Endlich K, Olden M, et al. Common variants in Mendelian kidney disease genes and their association with renal function. J Am Soc Nephrol. 2013 ;24(12):2105-17.

Ben-Avraham D, Karasik D, Verghese J, Lunetta KL, Smith JA, Eicher JD, Vered R, Deelen J, Arnold AM, Buchman AS, et al. The complex genetics of gait speed: genome-wide meta-analysis approach. Aging (Albany NY). 2017 ;9(1):209-246.

Sargurupremraj M, Soumaré A, Bis JC, Surakka I, Jürgenson T, Joly P, Knol MJ, Wang R, Yang Q, Satizabal CL, et al. Complexities of cerebral small vessel disease, blood pressure, and dementia relationship: new insights from genetics. medRxiv. 2023 .

Böger CA, Chen M-H, Tin A, Olden M, Köttgen A, de Boer IH, Fuchsberger C, O'Seaghdha CM, Pattaro C, Teumer A, et al. CUBN is a gene locus for albuminuria. J Am Soc Nephrol. 2011 ;22(3):555-70.

D

Winkler TW, Rasheed H, Teumer A, Gorski M, Rowan BX, Stanzick KJ, Thomas LF, Tin A, Hoppmann A, Chu AY, et al. Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals. Commun Biol. 2022 ;5(1):580.

van den Berg ME, Warren HR, Cabrera CP, Verweij N, Mifsud B, Haessler J, Bihlmeyer NA, Fu Y-P, Weiss S, Lin HJ, et al. Discovery of novel heart rate-associated loci using the Exome Chip. Hum Mol Genet. 2017 .

Bis JC, Sitlani C, Irvin R, Avery CL, Smith AVernon, Sun F, Evans DS, Musani SK, Li X, Trompet S, et al. Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium. PLoS One. 2015 ;10(10):e0140496.

E

Ganesh SK, Chasman DI, Larson MG, Guo X, Verwoert G, Bis JC, Gu X, Smith AV, Yang M-L, Zhang Y, et al. Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations. Am J Hum Genet. 2014 ;95(1):49-65.

Irie F, Fitzpatrick AL, Lopez OL, Kuller LH, Peila R, Newman AB, Launer LJ. Enhanced risk for Alzheimer disease in persons with type 2 diabetes and APOE epsilon4: the Cardiovascular Health Study Cognition Study. Arch Neurol. 2008 ;65(1):89-93.

Yang Y, Knol MJ, Wang R, Mishra A, Liu D, Luciano M, Teumer A, Armstrong N, Bis JC, Jhun MA, et al. Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI. Brain. 2022 .

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