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Journal Article
Sun C, Klein R, Wong TY. Age-related macular degeneration and risk of coronary heart disease and stroke: the Cardiovascular Health Study. Ophthalmology. 2009 ;116(10):1913-9.
Tikellis G, Sun C, Gorin MB, Klein R, Klein BEK, Larsen EKMarino, Siscovick DS, Hubbard LD, Wong TY. Apolipoprotein e gene and age-related maculopathy in older individuals: the cardiovascular health study. Arch Ophthalmol. 2007 ;125(1):68-73.
Sun C, Tikellis G, Liew G, Klein R, Larsen EKMarino, Wong TY. Apolipoprotein E gene and retinal microvascular signs in older people: the Cardiovascular Health Study. Mol Vis. 2007 ;13:2105-11.
Sun C, Tikellis G, Klein R, Steffens DC, Larsen EKMarino, Siscovick DS, Klein BEK, Wong TY. Are microvascular abnormalities in the retina associated with depression symptoms? The Cardiovascular Health Study. Am J Geriatr Psychiatry. 2007 ;15(4):335-43.
Xie J, M Ikram K, Cotch MFrances, Klein B, Varma R, Shaw JE, Klein R, Mitchell P, Lamoureux EL, Wong TYin. Association of Diabetic Macular Edema and Proliferative Diabetic Retinopathy With Cardiovascular Disease: A Systematic Review and Meta-analysis. JAMA Ophthalmol. 2017 ;135(6):586-593.
Longstreth W, Larsen EKMarino, Klein R, Wong TYin, A Sharrett R, Lefkowitz D, Manolio TA. Associations between findings on cranial magnetic resonance imaging and retinal photography in the elderly: the Cardiovascular Health Study. Am J Epidemiol. 2007 ;165(1):78-84.
Edwards MS, Wilson DB, Craven TE, Stafford J, Fried LF, Wong TY, Klein R, Burke GL, Hansen KJ. Associations between retinal microvascular abnormalities and declining renal function in the elderly population: the Cardiovascular Health Study. Am J Kidney Dis. 2005 ;46(2):214-24.
Sobrin L, Green T, Sim X, Jensen RA, Tai SE, Tay WTing, Wang JJin, Mitchell P, Sandholm N, Liu Y, et al. Candidate gene association study for diabetic retinopathy in persons with type 2 diabetes: the Candidate gene Association Resource (CARe). Invest Ophthalmol Vis Sci. 2011 ;52(10):7593-602.
Wong TYin, Larsen EKMarino, Klein R, Mitchell P, Couper DJ, Klein BEK, Hubbard LD, Siscovick DS, A Sharrett R. Cardiovascular risk factors for retinal vein occlusion and arteriolar emboli: the Atherosclerosis Risk in Communities & Cardiovascular Health studies. Ophthalmology. 2005 ;112(4):540-7.
Conley YP, Jakobsdottir J, Mah T, Weeks DE, Klein R, Kuller L, Ferrell RE, Gorin MB. CFH, ELOVL4, PLEKHA1 and LOC387715 genes and susceptibility to age-related maculopathy: AREDS and CHS cohorts and meta-analyses. Hum Mol Genet. 2006 ;15(21):3206-18.
Sun C, Tikellis G, Klein R, Steffens DC, Larsen EKMarino, Wong TY. Depressive symptoms and age-related macular degeneration in older people: the cardiovascular health study. Ophthalmic Epidemiol. 2007 ;14(3):127-33.
Holzinger ER, Verma SS, Moore CB, Hall M, De R, Gilbert-Diamond D, Lanktree MB, Pankratz N, Amuzu A, Burt A, et al. Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals. BioData Min. 2017 ;10:25.
Baker ML, Wang JJin, Rogers S, Klein R, Kuller LH, Larsen EK, Wong TYin. Early age-related macular degeneration, cognitive function, and dementia: the Cardiovascular Health Study. Arch Ophthalmol. 2009 ;127(5):667-73.
Klein R, Klein BEK, Marino EK, Kuller LH, Furberg C, Burke GL, Hubbard LD. Early age-related maculopathy in the cardiovascular health study. Ophthalmology. 2003 ;110(1):25-33.
M Ikram K, Sim X, Xueling S, Jensen RA, Cotch MFrances, Hewitt AW, Ikram AM, Wang JJin, Klein R, Klein BEK, et al. Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. PLoS Genet. 2010 ;6(10):e1001184.
Restrepo NA, Spencer KL, Goodloe R, Garrett TA, Heiss G, Bůzková P, Jorgensen N, Jensen RA, Matise TC, Hindorff LA, et al. Genetic determinants of age-related macular degeneration in diverse populations from the PAGE study. Invest Ophthalmol Vis Sci. 2014 ;55(10):6839-50.
Sim X, Jensen RA, M Ikram K, Cotch MFrances, Li X, Macgregor S, Xie J, Smith AVernon, Boerwinkle E, Mitchell P, et al. Genetic loci for retinal arteriolar microcirculation. PLoS One. 2013 ;8(6):e65804.
Sobrin L, Chong YHe, Fan Q, Gan A, Stanwyck LK, Kaidonis G, Craig JE, Kim J, Liao W-L, Huang Y-C, et al. Genetically Determined Plasma Lipid Levels and Risk of Diabetic Retinopathy: A Mendelian Randomization Study. Diabetes. 2017 ;66(12):3130-3141.
Jensen RA, Sim X, Li X, Cotch MFrances, M Ikram K, Holliday EG, Eiriksdottir G, Harris TB, Jonasson F, Klein BEK, et al. Genome-wide association study of retinopathy in individuals without diabetes. PLoS One. 2013 ;8(2):e54232.
Holliday EG, Smith AV, Cornes BK, Buitendijk GHS, Jensen RA, Sim X, Aspelund T, Aung T, Baird PN, Boerwinkle E, et al. Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. PLoS One. 2013 ;8(1):e53830.
McGeechan K, Liew G, Macaskill P, Irwig L, Klein R, Klein BEK, Wang JJin, Mitchell P, Vingerling JR, Dejong PTVM, et al. Meta-analysis: retinal vessel caliber and risk for coronary heart disease. Ann Intern Med. 2009 ;151(6):404-13.
Kim DHyun, Grodstein F, Newman AB, Chaves PHM, Odden MC, Klein R, Sarnak MJ, Lipsitz LA. Microvascular and Macrovascular Abnormalities and Cognitive and Physical Function in Older Adults: Cardiovascular Health Study. J Am Geriatr Soc. 2015 ;63(9):1886-93.
Pollack S, Igo RP, Jensen RA, Christiansen M, Li X, Cheng C-Y, C Y Ng M, Smith AV, Rossin EJ, Segrè AV, et al. Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control. Diabetes. 2019 ;68(2):441-456.
Jensen RA, Sim X, Smith AVernon, Li X, Jakobsdottir J, Cheng C-Y, Brody JA, Cotch MFrances, McKnight B, Klein R, et al. Novel Genetic Loci Associated With Retinal Microvascular Diameter. Circ Cardiovasc Genet. 2016 ;9(1):45-54.
McGeechan K, Liew G, Macaskill P, Irwig L, Klein R, Klein BEK, Wang JJin, Mitchell P, Vingerling JR, de Jong PTVM, et al. Prediction of incident stroke events based on retinal vessel caliber: a systematic review and individual-participant meta-analysis. Am J Epidemiol. 2009 ;170(11):1323-32.

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