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Journal Article
Sun C, Klein R, Wong TY. Age-related macular degeneration and risk of coronary heart disease and stroke: the Cardiovascular Health Study. Ophthalmology. 2009 ;116(10):1913-9.
Tikellis G, Sun C, Gorin MB, Klein R, Klein BEK, Larsen EKMarino, Siscovick DS, Hubbard LD, Wong TY. Apolipoprotein e gene and age-related maculopathy in older individuals: the cardiovascular health study. Arch Ophthalmol. 2007 ;125(1):68-73.
Sun C, Tikellis G, Liew G, Klein R, Larsen EKMarino, Wong TY. Apolipoprotein E gene and retinal microvascular signs in older people: the Cardiovascular Health Study. Mol Vis. 2007 ;13:2105-11.
Sun C, Tikellis G, Klein R, Steffens DC, Larsen EKMarino, Siscovick DS, Klein BEK, Wong TY. Are microvascular abnormalities in the retina associated with depression symptoms? The Cardiovascular Health Study. Am J Geriatr Psychiatry. 2007 ;15(4):335-43.
Cornes BK, Brody JA, Nikpoor N, Morrison AC, Chu H, Ahn BSoo, Wang S, Dauriz M, Barzilay JI, Dupuis J, et al. Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circ Cardiovasc Genet. 2014 ;7(3):374-382.
Edwards MS, Wilson DB, Craven TE, Stafford J, Fried LF, Wong TY, Klein R, Burke GL, Hansen KJ. Associations between retinal microvascular abnormalities and declining renal function in the elderly population: the Cardiovascular Health Study. Am J Kidney Dis. 2005 ;46(2):214-24.
Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, Pirruccello JP, Ripatti S, Chasman DI, Willer CJ, et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 2010 ;466(7307):707-13.
Sobrin L, Green T, Sim X, Jensen RA, Tai SE, Tay WTing, Wang JJin, Mitchell P, Sandholm N, Liu Y, et al. Candidate gene association study for diabetic retinopathy in persons with type 2 diabetes: the Candidate gene Association Resource (CARe). Invest Ophthalmol Vis Sci. 2011 ;52(10):7593-602.
Sun C, Tikellis G, Klein R, Steffens DC, Larsen EKMarino, Wong TY. Depressive symptoms and age-related macular degeneration in older people: the cardiovascular health study. Ophthalmic Epidemiol. 2007 ;14(3):127-33.
Agarwal I, Arnold A, Glazer NL, Barasch E, Djoussé L, Fitzpatrick AL, Gottdiener JS, Ix JH, Jensen RA, Kizer JR, et al. Fibrosis-related biomarkers and large and small vessel disease: the Cardiovascular Health Study. Atherosclerosis. 2015 ;239(2):539-46.
M Ikram K, Sim X, Xueling S, Jensen RA, Cotch MFrances, Hewitt AW, Ikram AM, Wang JJin, Klein R, Klein BEK, et al. Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. PLoS Genet. 2010 ;6(10):e1001184.
Restrepo NA, Spencer KL, Goodloe R, Garrett TA, Heiss G, Bůzková P, Jorgensen N, Jensen RA, Matise TC, Hindorff LA, et al. Genetic determinants of age-related macular degeneration in diverse populations from the PAGE study. Invest Ophthalmol Vis Sci. 2014 ;55(10):6839-50.
Sim X, Jensen RA, M Ikram K, Cotch MFrances, Li X, Macgregor S, Xie J, Smith AVernon, Boerwinkle E, Mitchell P, et al. Genetic loci for retinal arteriolar microcirculation. PLoS One. 2013 ;8(6):e65804.
Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang S-J, et al. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 2011 ;478(7367):103-9.
Jensen RA, Sim X, Li X, Cotch MFrances, M Ikram K, Holliday EG, Eiriksdottir G, Harris TB, Jonasson F, Klein BEK, et al. Genome-wide association study of retinopathy in individuals without diabetes. PLoS One. 2013 ;8(2):e54232.
Holliday EG, Smith AV, Cornes BK, Buitendijk GHS, Jensen RA, Sim X, Aspelund T, Aung T, Baird PN, Boerwinkle E, et al. Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. PLoS One. 2013 ;8(1):e53830.
Wessel J, Chu AY, Willems SM, Wang S, Yaghootkar H, Brody JA, Dauriz M, Hivert M-F, Raghavan S, Lipovich L, et al. Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. Nat Commun. 2015 ;6:5897.
McGeechan K, Liew G, Macaskill P, Irwig L, Klein R, Klein BEK, Wang JJin, Mitchell P, Vingerling JR, Dejong PTVM, et al. Meta-analysis: retinal vessel caliber and risk for coronary heart disease. Ann Intern Med. 2009 ;151(6):404-13.
Verhaaren BFJ, Debette S, Bis JC, Smith JA, M Ikram K, Adams HH, Beecham AH, Rajan KB, Lopez LM, Barral S, et al. Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI. Circ Cardiovasc Genet. 2015 ;8(2):398-409.
Pollack S, Igo RP, Jensen RA, Christiansen M, Li X, Cheng C-Y, C Y Ng M, Smith AV, Rossin EJ, Segrè AV, et al. Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control. Diabetes. 2019 ;68(2):441-456.
Jensen RA, Sim X, Smith AVernon, Li X, Jakobsdottir J, Cheng C-Y, Brody JA, Cotch MFrances, McKnight B, Klein R, et al. Novel Genetic Loci Associated With Retinal Microvascular Diameter. Circ Cardiovasc Genet. 2016 ;9(1):45-54.
Dastani Z, Hivert M-F, Timpson N, Perry JRB, Yuan X, Scott RA, Henneman P, Heid IM, Kizer JR, Lyytikäinen L-P, et al. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet. 2012 ;8(3):e1002607.
McGeechan K, Liew G, Macaskill P, Irwig L, Klein R, Klein BEK, Wang JJin, Mitchell P, Vingerling JR, de Jong PTVM, et al. Prediction of incident stroke events based on retinal vessel caliber: a systematic review and individual-participant meta-analysis. Am J Epidemiol. 2009 ;170(11):1323-32.
Boland LL, Shahar E, Wong TY, Klein R, Punjabi N, Robbins JA, Newman AB. Sleep-disordered breathing is not associated with the presence of retinal microvascular abnormalities: the Sleep Heart Health Study. Sleep. 2004 ;27(3):467-73.
Lye WKit, Paterson E, Patterson CC, Maxwell AP, Abdul RBanu Binte, Tai SE, Cheng CYu, Kayama T, Yamashita H, Sarnak M, et al. A systematic review and participant-level meta-analysis found little association of retinal microvascular caliber and reduced kidney function. Kidney Int. 2020 .