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2021

Jones G, Trajanoska K, Santanasto AJ, Stringa N, Kuo CL, Atkins JL, Lewis JR, Duong T, Hong S, Biggs ML, et al. {Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women. Nat Commun. 2021 ;12:654.

Lumbers RT, Shah S, Lin H, Czuba T, Henry A, Swerdlow DI, Malarstig A, Andersson C, Verweij N, Holmes MV, et al. {The genomics of heart failure: design and rationale of the HERMES consortium. ESC Heart Fail. 2021 .

Koch M, Aroner SA, Fitzpatrick AL, Longstreth WT, Furtado JD, Mukamal KJ, Jensen MK. HDL (High-Density Lipoprotein) Subspecies, Prevalent Covert Brain Infarcts, and Incident Overt Ischemic Stroke: Cardiovascular Health Study. Stroke. 2021 :STROKEAHA121034299.

Harrington LB, Ehlert AN, Thacker EL, Jenny NS, Lopez O, Cushman M, Fitzpatrick A, Mukamal KJ, Jensen MK. Hemostatic factor levels and cognitive decline in older adults: The Cardiovascular Health Study. J Thromb Haemost. 2021 .

Yang Y, Bartz TM, Brown MR, Guo X, Zilhão NR, Trompet S, Weiss S, Yao J, Brody JA, deFilippi CR, et al. Identification of Functional Genetic Determinants of Cardiac Troponin T and I in a Multiethnic Population and Causal Associations With Atrial Fibrillation. Circ Genom Precis Med. 2021 ;14(6):e003460.

Sarnowski C, Chen H, Biggs ML, Wassertheil-Smoller S, Bressler J, Irvin MR, Ryan KA, Karasik D, Arnett DK, Cupples AL, et al. Identification of novel and rare variants associated with handgrip strength using whole genome sequence data from the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program. PLoS One. 2021 ;16(7):e0253611.

He Z, Liu L, Wang C, Le Guen Y, Lee J, Gogarten S, Lu F, Montgomery S, Tang H, Silverman EK, et al. Identification of putative causal loci in whole-genome sequencing data via knockoff statistics. Nat Commun. 2021 ;12(1):3152.

Shah M, Rodriguez CJ, Bartz TM, Lyles MF, Kizer JR, Aurigemma GP, Gardin JM, Gottdiener JS. Incidence, Determinants and Mortality of Heart Failure Associated With Medical-Surgical Procedures in Patients ≥ 65 Years of Age (from the Cardiovascular Health Study). Am J Cardiol. 2021 ;153:71-78.

Pellegrini CN, Bůzková P, Lichtenstein AH, Matthan NR, Ix JH, Siscovick DS, Heckbert SR, Tracy RP, Mukamal KJ, Djoussé L, et al. Individual non-esterified fatty acids and incident atrial fibrillation late in life. Heart. 2021 .

Lee Y, Nemet I, Wang Z, Lai HTM, Otto MC de Olive, Lemaitre RN, Fretts AM, Sotoodehnia N, Budoff M, DiDonato JA, et al. Longitudinal Plasma Measures of Trimethylamine N-Oxide and Risk of Atherosclerotic Cardiovascular Disease Events in Community-Based Older Adults. J Am Heart Assoc. 2021 :e020646.

Schlosser P, Tin A, Matias-Garcia PR, Thio CHL, Joehanes R, Liu H, Weihs A, Yu Z, Hoppmann A, Grundner-Culemann F, et al. Meta-analyses identify DNA methylation associated with kidney function and damage. Nat Commun. 2021 ;12(1):7174.

Portilla-Fernández E, Hwang S-J, Wilson R, Maddock J, W Hill D, Teumer A, Mishra PP, Brody JA, Joehanes R, Ligthart S, et al. Meta-analysis of epigenome-wide association studies of carotid intima-media thickness. Eur J Epidemiol. 2021 .

Sun D, Richard M, Musani SK, Sung YJu, Winkler TW, Schwander K, Chai JFang, Guo X, Kilpeläinen TO, Vojinovic D, et al. Multi-Ancestry Genome-wide Association Study Accounting for Gene-Psychosocial Factor Interactions Identifies Novel Loci for Blood Pressure Traits. HGG Adv. 2021 ;2(1).

Wang H, Noordam R, Cade BE, Schwander K, Winkler TW, Lee J, Sung YJu, Bentley AR, Manning AK, Aschard H, et al. Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure. Mol Psychiatry. 2021 .

Jhun MA, Mendelson M, Wilson R, Gondalia R, Joehanes R, Salfati E, Zhao X, Braun KVE, Do AN, Hedman ÅK, et al. {A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids. Nat Commun. 2021 ;12:3987.

Lu Y, Dimitrov L, Chen S-H, Bielak LF, Bis JC, Feitosa MF, Lu L, Kavousi M, Raffield LM, Smith AV, et al. Multiethnic Genome-Wide Association Study of Subclinical Atherosclerosis in Individuals With Type 2 Diabetes. Circ Genom Precis Med. 2021 ;14(4):e003258.

Beauchamp EM, Leventhal M, Bernard E, Hoppe ER, Todisco G, Creignou M, Gallì A, Castellano CA, McConkey M, Tarun A, et al. is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing. Blood Cancer Discov. 2021 ;2(5):500-517.

Qian F, Korat AVArdisso, Imamura F, Marklund M, Tintle N, Virtanen JK, Zhou X, Bassett JK, Lai H, Hirakawa Y, et al. n-3 Fatty Acid Biomarkers and Incident Type 2 Diabetes: An Individual Participant-Level Pooling Project of 20 Prospective Cohort Studies. Diabetes Care. 2021 ;44:1133–1142.

Delaney JAC, Olson NC, Sitlani CM, Fohner AE, Huber SA, Landay AL, Heckbert SR, Tracy RP, Psaty BM, Feinstein M, et al. Natural killer cells, gamma delta T cells and classical monocytes are associated with systolic blood pressure in the multi-ethnic study of atherosclerosis (MESA). BMC Cardiovasc Disord. 2021 ;21(1):45.

Walther CP, Ix JH, Biggs ML, Kizer JR, Navaneethan SD, Djoussé L, Mukamal KJ. Nonesterified Fatty Acids and Kidney Function Decline in Older Adults: Findings From the Cardiovascular Health Study. Am J Kidney Dis. 2021 .

Hwang PH, Longstreth WT, Thielke SM, Francis CE, Carone M, Kuller LH, Fitzpatrick AL. Ophthalmic conditions associated with dementia risk: The Cardiovascular Health Study. Alzheimers Dement. 2021 .

Pandey A, Mehta A, Paluch A, Ning H, Carnethon MR, Allen NB, Michos ED, Berry JD, Lloyd-Jones DM, Wilkins JT. Performance of the American Heart Association/American College of Cardiology Pooled Cohort Equations to Estimate Atherosclerotic Cardiovascular Disease Risk by Self-reported Physical Activity Levels. JAMA Cardiol. 2021 ;6(6):690-696.

Trompet S, Postmus I, Warren HR, Noordam R, Smit RAJ, Theusch E, Li X, Arsenault B, Chasman DI, Hitman GA, et al. The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction. Front Pharmacol. 2021 ;12:679857.

Karunananthan S, Moodie EEM, Bergman H, Payette H, Diehr PH, Wolfson C. Physical Function and Survival in Older Adults: A longitudinal study accounting for time-varying effects. Arch Gerontol Geriatr. 2021 ;96:104440.

Fretts AM, Jensen PN, Hoofnagle AN, McKnight B, Howard BV, Umans J, Sitlani CM, Siscovick DS, King IB, Djoussé L, et al. Plasma Ceramides containing Saturated Fatty Acids are Associated with Risk of Type 2 Diabetes. J Lipid Res. 2021 :100119.

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