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Evaluation of a method for fitting a semi-Markov process model in the presence of left-censored spells using the Cardiovascular Health Study.
Tuesday,2012-11-06 12:10 America/Los_Angeles — eenright
| Title | Evaluation of a method for fitting a semi-Markov process model in the presence of left-censored spells using the Cardiovascular Health Study. |
| Publication Type | Journal Article |
| Year of Publication | 2008 |
| Authors | Cai, L, Schenker, N, Lubitz, J, Diehr, P, Arnold, A, Fried, LP |
| Journal | Stat Med |
| Volume | 27 |
| Issue | 26 |
| Pagination | 5509-24 |
| Date Published | 2008 Nov 20 |
| ISSN | 0277-6715 |
| Keywords | Activities of Daily Living, Aged, Aged, 80 and over, Cardiovascular Diseases, Cardiovascular System, Data Interpretation, Statistical, Disease Progression, Female, Humans, Longitudinal Studies, Male, Markov Chains, Models, Statistical, Stochastic Processes, Time Factors |
| Abstract | <p>We used a longitudinal data set covering 13 years from the Cardiovascular Health Study to evaluate the properties of a recently developed approach to deal with left censoring that fits a semi-Markov process (SMP) model by using an analog to the stochastic EM algorithm--the SMP-EM approach. It appears that the SMP-EM approach gives estimates of duration-dependent probabilities of health changes similar to those obtained by using SMP models that have the advantage of actual duration data. SMP-EM estimates of duration-dependent transition probabilities also appear more accurate and less variable than multi-state life table estimates.</p> |
| DOI | 10.1002/sim.3382 |
| Alternate Journal | Stat Med |
| PubMed ID | 18712777 |
| PubMed Central ID | PMC2878178 |
| Grant List | U01 HL080295-04 / HL / NHLBI NIH HHS / United States U01 HL080295 / HL / NHLBI NIH HHS / United States U01 HL080295-01 / HL / NHLBI NIH HHS / United States U01 HL080295-03 / HL / NHLBI NIH HHS / United States U01 HL080295-02 / HL / NHLBI NIH HHS / United States |