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Hematological and biochemical laboratory values in older Cardiovascular Health Study participants.
Tuesday,2012-11-06 12:26 America/Los_Angeles — eenright
| Title | Hematological and biochemical laboratory values in older Cardiovascular Health Study participants. |
| Publication Type | Journal Article |
| Year of Publication | 1995 |
| Authors | Robbins, J, Wahl, P, Savage, P, Enright, P, Powe, N, Lyles, M |
| Journal | J Am Geriatr Soc |
| Volume | 43 |
| Issue | 8 |
| Pagination | 855-9 |
| Date Published | 1995 Aug |
| ISSN | 0002-8614 |
| Keywords | Age Factors, Aged, Analysis of Variance, California, Cardiovascular Diseases, Cohort Studies, Female, Health Status, Humans, Male, Maryland, Middle Aged, North Carolina, Pennsylvania, Reference Values, Risk Factors, Sex Characteristics |
| Abstract | <p><b>OBJECTIVE: </b>To define reference hematologic and biochemical lab values in older individuals.</p><p><b>DESIGN: </b>Randomly selected, age- and gender-stratified participants.</p><p><b>SETTING: </b>Visits by participants to four research clinics.</p><p><b>PATIENTS: </b>A total of 5201 participants in the Cardiovascular Health Study, an observational study of older Medicare-eligible individuals living at home.</p><p><b>MEASUREMENT: </b>Information about health status, previous illness, and medication use was obtained from participants and/or their MDs. This information was used to define a healthy subset of the population. Blood samples were obtained for Cholesterol, HDL and LDL cholesterol, fasting and 2-hour postload glucose and insulin, fibrinogen, factors VII and VIII, potassium, creatinine, albumin, uric acid, white blood count, hematocrit, hemoglobin, and platelet count.</p><p><b>RESULTS: </b>Significant differences were found for age group and/or gender for all mean values. Many tests were significantly different from the generally accepted reference ranges used in clinical laboratories.</p><p><b>CONCLUSIONS: </b>In some situations accepted laboratory norms for the general population can not be extrapolated to older adults. There are implications for both research and clinical practice.</p> |
| Alternate Journal | J Am Geriatr Soc |
| PubMed ID | 7636091 |