Title | Cognitive test performance and presence of subclinical cardiovascular disease in the cardiovascular health study. |
Publication Type | Journal Article |
Year of Publication | 2000 |
Authors | Saxton, J, Ratcliff, G, Newman, A, Belle, S, Fried, L, Yee, J, Kuller, L |
Journal | Neuroepidemiology |
Volume | 19 |
Issue | 6 |
Pagination | 312-9 |
Date Published | 2000 Nov-Dec |
ISSN | 0251-5350 |
Keywords | Aged, Cardiovascular Diseases, Cognition Disorders, Female, Humans, Hypertension, Male, Severity of Illness Index, Wechsler Scales |
Abstract | <p>The purpose of the present study was to investigate the relationship between performance on a comprehensive battery of neuropsychological tests and the presence of clinical, subclinical or no cardiovascular disease in an elderly community-dwelling population. The results confirm previous reports of significant associations of age, education and gender with test performance. When performance was examined controlling for these variables, significant associations of disease group were seen with five measures emphasizing speed of performance; Parts A and B of the Trail Making Test, the WAIS-R Digit Symbol and Block Design subtests and category verbal fluency. These results add to the evidence that, in addition to other health implications, cardiovascular disease is related to cognitive functioning in the elderly even at subclinical levels.</p> |
DOI | 10.1159/000026270 |
Alternate Journal | Neuroepidemiology |
PubMed ID | 11060505 |
Grant List | MH 46643 / MH / NIMH NIH HHS / United States N01-HC-85080 / HC / NHLBI NIH HHS / United States N01-HC-95079 / HC / NHLBI NIH HHS / United States |