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Development and validation of a brief dementia screening indicator for primary care.
Thursday,2014-04-03 12:56 America/Los_Angeles — eenright
| Title | Development and validation of a brief dementia screening indicator for primary care. |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Barnes, DE, Beiser, AS, Lee, A, Langa, KM, Koyama, A, Preis, SR, Neuhaus, J, McCammon, RJ, Yaffe, K, Seshadri, S, Haan, MN, Weir, DR |
| Journal | Alzheimers Dement |
| Volume | 10 |
| Issue | 6 |
| Pagination | 656-665.e1 |
| Date Published | 2014 Nov |
| ISSN | 1552-5279 |
| Keywords | Aged, Cohort Studies, Dementia, Female, Humans, Male, Mass Screening, Predictive Value of Tests, Primary Health Care, Proportional Hazards Models, Risk Assessment |
| Abstract | <p><b>BACKGROUND: </b>Detection of "any cognitive impairment" is mandated as part of the Medicare annual wellness visit, but screening all patients may result in excessive false positives.</p><p><b>METHODS: </b>We developed and validated a brief Dementia Screening Indicator using data from four large, ongoing cohort studies (the Cardiovascular Health Study [CHS]; the Framingham Heart Study [FHS]; the Health and Retirement Study [HRS]; the Sacramento Area Latino Study on Aging [SALSA]) to help clinicians identify a subgroup of high-risk patients to target for cognitive screening.</p><p><b>RESULTS: </b>The final Dementia Screening Indicator included age (1 point/year; ages, 65-79 years), less than 12 years of education (9 points), stroke (6 points), diabetes mellitus (3 points), body mass index less than 18.5 kg/m(2) (8 points), requiring assistance with money or medications (10 points), and depressive symptoms (6 points). Accuracy was good across the cohorts (Harrell's C statistic: CHS, 0.68; FHS, 0.77; HRS, 0.76; SALSA, 0.78).</p><p><b>CONCLUSIONS: </b>The Dementia Screening Indicator is a simple tool that may be useful in primary care settings to identify high-risk patients to target for cognitive screening.</p> |
| DOI | 10.1016/j.jalz.2013.11.006 |
| Alternate Journal | Alzheimers Dement |
| PubMed ID | 24491321 |
| PubMed Central ID | PMC4119094 |
| Grant List | AG033040 / AG / NIA NIH HHS / United States N01-HC-25195 / HC / NHLBI NIH HHS / United States AG013846 / AG / NIA NIH HHS / United States R01 NS017950 / NS / NINDS NIH HHS / United States K24-AG031155 / AG / NIA NIH HHS / United States N01HC85239 / HC / NHLBI NIH HHS / United States N01HC85080 / HC / NHLBI NIH HHS / United States U01 AG009740 / AG / NIA NIH HHS / United States AG12975 / AG / NIA NIH HHS / United States AG033193 / AG / NIA NIH HHS / United States DK60753 / DK / NIDDK NIH HHS / United States N01HC85081 / HC / NHLBI NIH HHS / United States N01HC85079 / HC / NHLBI NIH HHS / United States K24 AG031155 / AG / NIA NIH HHS / United States R01 AG008122 / AG / NIA NIH HHS / United States R01 AG033193 / AG / NIA NIH HHS / United States N01HC85086 / HC / NHLBI NIH HHS / United States N01HC85082 / HC / NHLBI NIH HHS / United States R01 AG012975 / AG / NIA NIH HHS / United States AG081220 / AG / NIA NIH HHS / United States NS017950 / NS / NINDS NIH HHS / United States HL080295 / HL / NHLBI NIH HHS / United States N01HC85083 / HC / NHLBI NIH HHS / United States AG023629 / AG / NIA NIH HHS / United States HHSN268201200036 C / / PHS HHS / United States N01 HC55222 / HC / NHLBI NIH HHS / United States |