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Consumption of Caffeinated Products and Cardiac Ectopy.
Thursday,2016-03-31 14:49 America/Los_Angeles — zdrager
| Title | Consumption of Caffeinated Products and Cardiac Ectopy. |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Dixit, S, Stein, PK, Dewland, TA, Dukes, JW, Vittinghoff, E, Heckbert, SR, Marcus, GM |
| Journal | J Am Heart Assoc |
| Volume | 5 |
| Issue | 1 |
| Date Published | 2016 Jan |
| ISSN | 2047-9980 |
| Abstract | <p><b>BACKGROUND: </b>Premature cardiac contractions are associated with increased morbidity and mortality. Though experts associate premature atrial contractions (PACs) and premature ventricular contractions (PVCs) with caffeine, there are no data to support this relationship in the general population. As certain caffeinated products may have cardiovascular benefits, recommendations against them may be detrimental.</p><p><b>METHODS AND RESULTS: </b>We studied Cardiovascular Health Study participants with a baseline food frequency assessment, 24-hour ambulatory electrocardiography (Holter) monitoring, and without persistent atrial fibrillation. Frequencies of habitual coffee, tea, and chocolate consumption were assessed using a picture-sort food frequency survey. The main outcomes were PACs/h and PVCs/hour. Among 1388 participants (46% male, mean age 72 years), 840 (61%) consumed ≥1 caffeinated product per day. The median numbers of PACs and PVCs/h and interquartile ranges were 3 (1-12) and 1 (0-7), respectively. There were no differences in the number of PACs or PVCs/h across levels of coffee, tea, and chocolate consumption. After adjustment for potential confounders, more frequent consumption of these products was not associated with ectopy. In examining combined dietary intake of coffee, tea, and chocolate as a continuous measure, no relationships were observed after multivariable adjustment: 0.48% fewer PACs/h (95% CI -4.60 to 3.64) and 2.87% fewer PVCs/h (95% CI -8.18 to 2.43) per 1-serving/week increase in consumption.</p><p><b>CONCLUSIONS: </b>In the largest study to evaluate dietary patterns and quantify cardiac ectopy using 24-hour Holter monitoring, we found no relationship between chronic consumption of caffeinated products and ectopy.</p> |
| DOI | 10.1161/JAHA.115.002503 |
| Alternate Journal | J Am Heart Assoc |
| PubMed ID | 26813889 |
| PubMed Central ID | PMC4859368 |
| Grant List | HHSN268200800007C / / PHS HHS / United States HHSN268201200036C / / PHS HHS / United States N01HC55222 / HC / NHLBI NIH HHS / United States N01HC85079 / HC / NHLBI NIH HHS / United States N01HC85080 / HC / NHLBI NIH HHS / United States N01HC85081 / HC / NHLBI NIH HHS / United States N01HC85082 / HC / NHLBI NIH HHS / United States N01HC85083 / HC / NHLBI NIH HHS / United States N01HC85086 / HC / NHLBI NIH HHS / United States R01AG023629 / AG / NIA NIH HHS / United States TL1 TR000144 / TR / NCATS NIH HHS / United States U01HL080295 / HL / NHLBI NIH HHS / United States |