Title | {The genomics of heart failure: design and rationale of the HERMES consortium |
Publication Type | Journal Article |
Year of Publication | 2021 |
Authors | Lumbers, RT, Shah, S, Lin, H, Czuba, T, Henry, A, Swerdlow, DI, Malarstig, A, Andersson, C, Verweij, N, Holmes, MV, Ärnlöv, J, Svensson, P, Hemingway, H, Sallah, N, Almgren, P, Aragam, KG, Asselin, G, Backman, JD, Biggs, ML, Bloom, HL, Boersma, E, Brandimarto, J, Brown, MR, La Rocca, HPBrunner, Carey, DJ, Chaffin, MD, Chasman, DI, Chazara, O, Chen, X, Chen, X, Chung, JH, Chutkow, W, Cleland, JGF, Cook, JP, de Denus, S, Dehghan, A, Delgado, GE, Denaxas, S, Doney, AS, Dörr, M, Dudley, SC, Engström, G, Esko, T, Fatemifar, G, Felix, SB, Finan, C, Ford, I, Fougerousse, F, Fouodjio, R, Ghanbari, M, Ghasemi, S, Giedraitis, V, Giulianini, F, Gottdiener, JS, Gross, S, Guðbjartsson, DF, Gui, H, Gutmann, R, Haggerty, CM, van der Harst, P, Hedman, ÅK, Helgadottir, A, Hillege, H, Hyde, CL, Jacob, J, Jukema, JW, Kamanu, F, Kardys, I, Kavousi, M, Khaw, KT, Kleber, ME, Køber, L, Koekemoer, A, Kraus, B, Kuchenbaecker, K, Langenberg, C, Lind, L, Lindgren, CM, London, B, Lotta, LA, Lovering, RC, Luan, J, Magnusson, P, Mahajan, A, Mann, D, Margulies, KB, Marston, NA, März, W, McMurray, JJV, Melander, O, Melloni, G, Mordi, IR, Morley, MP, Morris, AD, Morris, AP, Morrison, AC, Nagle, MW, Nelson, CP, Newton-Cheh, C, Niessner, A, Niiranen, T, Nowak, C, O'Donoghue, ML, Owens, AT, Palmer, CNA, Pare, G, Perola, M, Perreault, LL, Portilla-Fernandez, E, Psaty, BM, Rice, KM, Ridker, PM, Romaine, SPR, Roselli, C, Rotter, JI, Ruff, CT, Sabatine, MS, Salo, P, Salomaa, V, van Setten, J, Shalaby, AA, Smelser, DT, Smith, NL, Stefansson, K, Stender, S, Stott, DJ, Sveinbjornsson, G, Tammesoo, ML, Tardif, JC, Taylor, KD, Teder-Laving, M, Teumer, A, Thorgeirsson, G, Thorsteinsdottir, U, Torp-Pedersen, C, Trompet, S, Tuckwell, D, Tyl, B, Uitterlinden, AG, Vaura, F, Veluchamy, A, Visscher, PM, Völker, U, Voors, AA, Wang, X, Wareham, NJ, Weeke, PE, Weiss, R, White, HD, Wiggins, KL, Xing, H, Yang, J, Yang, Y, Yerges-Armstrong, LM, Yu, B, Zannad, F, Zhao, F, Wilk, JB, Holm, H, Sattar, N, Lubitz, SA, Lanfear, DE, Shah, S, Dunn, ME, Wells, QS, Asselbergs, FW, Hingorani, AD, Dubé, MP, Samani, NJ, Lang, CC, Cappola, TP, Ellinor, PT, Vasan, RS, Smith, JG |
Journal | ESC Heart Fail |
Date Published | Sep |
Abstract | The HERMES (HEart failure Molecular Epidemiology for Therapeutic targetS) consortium aims to identify the genomic and molecular basis of heart failure.\ under an additive genetic model.\ HERMES is a global collaboration aiming to (i) identify the genetic determinants of heart failure; (ii) generate insights into the causal pathways leading to heart failure and enable genetic approaches to target prioritization; and (iii) develop genomic tools for disease stratification and risk prediction. |