Importance: High throughput genotyping and sequencing across the genome may identify secondary ... genetic findings with evidence of association with disease risk or treatment response. The population prevalence and clinical significance of secondary findings is largely ...
... Apolipoprotein E is a glycoprotein best known as a mediator and regulator of lipid transport and uptake. The APOE-ε4 ... Study, Long Life Family Study, Cardiovascular Health Study, Health-ABC Study). Setting and participants: ... to other ethnicities, and multiple measurements of serum lipids could better capture their effect on survival. ...