Objective: To examine whether dietary intake and sleep duration modify the association between ... CRY2 -rs11605924, MTNR1B -rs1387153, rs10830963; and NR1D1 -rs2314339) and glycemic traits, fasting glucose (FG) and HOMA-IR, ...
... Circulating omega-3 fatty acids may reduce cardiovascular disease risk, and genetic variants are associated with concentrations of ... : We evaluated interactions between common genetic variants and fatty acid intakes for the outcomes of circulating ...
... cannot be synthesized by humans, are linked to adverse health outcomes. While TFA are initially obtained from ... (n=8,013) that incorporated genome-wide association studies and objective biomarkers (erythrocyte phospholipids or plasma phospholipids) of circulating TFA, ...
... of these variants with obesity traits. Methods: 32 BMI- and 14 waist-hip ratio (WHR)-associated SNPs were genotyped ... predisposition and obesity traits were stronger with a healthier diet. Interpretation: While these data show modest ... are small, which likely limits their relevance for public health interventions. dietary patterns Genetics obesity ...
... the rate-limiting step of de novo sphingolipid synthesis, and CERS4 (ceramide synthase 4). The SPTLC3 variant at ... was associated with higher levels of 20:0 ( p = 2.65x10-40) and in analyses adjusted for 20:0, with lower levels of 22:0 (behenic acid, p = 4.22x10-26) and 24:0 (lignoceric acid, p = 3.20x10-21). These novel ...