Importance: Disease burden does not account fully for functional status, ... adaptation. Adaptive factors may be translatable to promote healthy aging. Objective: To ascertain if adapters ... 3 groups by extent of disease, assessed non-invasively, and vigor/frailty: expected agers (N=1458, extent of disease ...
biomarkers 1. Introduction [Rationale and background]: Background: In CHS, we began to look at methods to combine markers of aging and age-related diseaseand developed the concept of a subclinical, ... emphasizing the need to measure multiple systems to define healthy aging. In total, these observations suggest that ...
... we began to look at methods to combine markers of aging and age-related diseaseand developed the concept of a subclinical, ... emphasizing the need to measure multiple systems to define healthy aging. In total, these observations suggest that ...