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... uncertainty whether the associations of chronic kidney disease (CKD) with mortality and end-stage renal disease (ESRD) differ between men and women. Objective: To assess the presence of a gender ...- 2014-05-20 11:27 - 1 comment
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... uncertainty whether the associations of chronic kidney disease (CKD) with mortality and end-stage renal disease (ESRD) differ between men and women. Objective: To assess the presence of a gender ...- 2014-03-13 14:40
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... a drug target can mimic pharmacological action of a drug and can be used to infer the probable clinical efficacy of ... also tested the association of carrier status with plasma lipids. RESULTS: In the discovery study, we identified four ... sequencing in the discovery study, and the Women’s Health Initiative (WHI). 14 All participants underwent a ...- 2014-05-13 21:58
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... The compression of morbidity paradigm argues that healthy lifestyle factors can postpone the onset of morbidity to a ... factors on functional health (Years of Able Life, YAL) and life expectancy (Years of Life, YOL) to describe their ...- 2014-02-22 08:34 - 1 comment
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ABSTRACT Coagulation factor VIII and von Willebrand factor (vWF) are important components of the coagulation ... vWF antigen (vWF:Ag) are risk factors for cardiovascular disease and venous thromboembolism. Beyond associations with ...- 2014-04-04 22:11
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Background Candidate gene and genome-wide association studies have ... targets for therapy. Funding The National Institutes of Health (NIH) National Heart, Lung, and Blood Institute ... RC2-HL-102923 (LungGO), and RC2-HL-102924 (Women's Health Initiative Sequencing Project, WHISP). Exome ...- 2014-01-06 11:00
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Elevated fasting glucose (FG) and insulin (FI) levels are both capturing pathways that lead to type 2 diabetes (T2D) – hyperglycaemia and insulin resistance. To test the role of coding variation ... we used the HumanExome BeadChip in up to 60,564 individuals and followed up findings in 14,494 (T2D) cases and 80,277 ...- 2014-04-02 11:34
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Fibrinogen, coagulation factors VII (FVII) and VIII (FVIII) and its carrier von Willebrand factor (vWF) play key roles in hemostasis. Common ...- 2014-12-20 20:29 - 1 comment
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Objective: To examine whether dietary intake and sleep duration modify the association between ... CRY2 -rs11605924, MTNR1B -rs1387153, rs10830963; and NR1D1 -rs2314339) and glycemic traits, fasting glucose (FG) and HOMA-IR, ...- 2014-10-21 14:01 - 1 comment
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Background: The short and long-term risks of cardiovascular disease (CVD) after infection are poorly understood. ... cohorts with 21-year follow-up: Cardiovascular Health Study (CHS, n=5,888, initial age 65 years or older) ...- 2014-04-02 07:18