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... When studying the association between physical function and survival in older adults, one of the challenges is the ... while accounting for demographic, lifestyle and health characteristics. Methods: Physical function and other ... strength are believed to capture the complexity of multiple diseases and provide a global measure of health. 2 There is ...- 2014-11-07 09:51 - 8 comments
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biomarkers 1. Introduction [Rationale and background]: Background: In CHS, we began to look at methods to combine markers of aging and age-related disease and developed the concept of a subclinical, ... emphasizing the need to measure multiple systems to define healthy aging. In total, these observations suggest that ...- 2014-03-15 12:58 - 4 comments
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... (CABG) is a successful treatment for coronary artery disease increasingly used in elderly patients. However, ... We conducted a systematic review, prospective study and meta-analyses to investigate the long-term association ... cohort study and meta-analyses Setting: The Cardiovascular Health Study (CHS) data were collected from four US ...- 2014-08-29 02:57 - 7 comments
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... elucidate the practical limitations of methods to estimate randomized controlled trial effects from observational data. ... We used data from 5,294 participants in the Cardiovascular Health Study from 1989-2004. For non-cardiovascular ... death from CHD) Covariates: Cardiovascular risk variables : lipids (total cholesterol, HDL, LDL, triglycerides), ...- 2014-12-15 10:05 - 5 comments
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Background: Recent evidence suggests that a healthy lifestyle among older adults can compress the period ... lifestyle factors could also influence hospital admission and stay among older adults during their last five years of life, after accounting for cumulative chronic disease burden. Methods: We examined data from 3780 ...- 2014-05-28 11:09 - 4 comments
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... (EPA; 20:5n-3), docosapentaenoic (DPA; 22:5n-3), and docosahexaenoic acid (DHA; 22:6n-3), and plant-derived ... MI events, with omega-3 measures in plasma, phospholipids, cholesterol esters, and adipose. In continuous (90th ... biomarkers, is associated with CHD is a key public health ...- 2014-02-18 09:14 - 2 comments
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... uncertainty whether the associations of chronic kidney disease (CKD) with mortality and end-stage renal disease (ESRD) differ between men and women. Objective: To assess the presence of a gender ...- 2014-05-20 11:27 - 1 comment
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... SNPs risk score analysis pathway-based analysis medicare health care costs health care spending Introduction Growing ... of the public health care payers such as Medicare and Medicaid but its highly-skewed distribution also places ... scores include those for diabetes, obesity, hypertension, lipids, coronary artery disease, and cancer. SNPs not ...- 2014-08-18 18:06 - 5 comments
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Background: Despite being frequently prescribed and their well-established cardio-protective benefits, the ... data from 4,952 participants enrolled in the Cardiovascular health study from 1989-99 to 1999/2000. We conceptualized ... attainment, alcohol intake, physical activity level; lipids: total cholesterol, HDL, LDL, triglycerides; ...- 2014-05-07 08:46 - 8 comments
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... contractions are associated with increased morbidity and mortality. Though expert consensus panels associate ... Participants — All 1,388 adults in the Cardiovascular Health Study who completed a baseline food frequency ... to be harmless in the absence of known cardiovascular disease or symptoms; however, there is now evidence to ...- 2014-11-20 09:48 - 6 comments