... factors of the Framingham Risk Score , and expanded this model with mean common CIMT, and then additionally with ... the carotid bifurcation or internal carotid artery. For all models, 10-year risks to develop a myocardial infarction or ... We examined discrimination and calibration of the 3 models and calculated the net reclassification improvement ...
... and coronary artery disease) alone was 0.73. The final model included all components of the Health ABC Heart ... 95% CI, 0.90-0.99; p=0.01). The C-statistic for the final model was 0.77 which was significantly improved over the Health ABC model alone (p=0.0002). heart failure heart rate variability ...
... the following variables/phenotypes for inclusion in model predicting mortality over 10+ years, as available in ... blood pressure Fasting glucose Analysis plan: Use Cox models and study visit to ensure mean follow up of at least ... backward selection to identify variables for retaining in model Sub-analyses will test model in shorter (1-4 years) vs ...
... BeadChip and the percentage of methylation was modeled in linear mixed effect models with adjustment for potential confounders. To ... relevance of the replicated inflammation-related epigenetic modifications, we examined the association between ...
... medication (bisphosphonates, selective estrogen receptor modulators (SERMs), parathyroid hormone, calcitonin, calcium ... using independent participant data. Two multivariate models will be conducted: one adjusting for age, gender and ... [ 1 ]. We will further add baseline BMD to the multivariate models to assess attenuation of a relationship between TSH ...