Importance: Premature atrial contractions (PACs) and premature ventricular contractions (PVCs) quantified by ... Observational cohort study Setting: The Cardiovascular Health Study (CHS) as the primary cohort, and the ... and ultimately preventive therapies for these important diseases. premature ventricular contractions premature ...
... resistance BACKGROUND & RATIONALE The NLRP3 inflammasome and interleukin-1β (IL-1β) play a critical role in obesity ... via AMPK (7). We are interested in components of the NLRP3 and IL-1 signalling cascades within the context of diet ... of priming IL-1 signalling are IL-1b, IL-18, NLRP3, ASC and Caspase-1. By identifying the SNP’s associated with ...