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... processed food (UPF) consumption is associated with adverse health outcomes. Plant- and animal-sourced UPF have a unique nutritional composition ... associated with greater prevalence and incidence of chronic diseases including cancer (5), hypertension (6,7), and ...- 2024-12-10 21:05 - 2 comments
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neurofilament light chain healthy life years of able life • Introduction [Rationale and background] As people worldwide are living longer, the ... living (ADLs) may lead to poor quality of life 4,5 , worse health outcome 6 , and higher risk of depression 7 . Longer ...- 2024-12-18 08:08 - 7 comments
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cardiovascular disease (CVD) phenylacetylglutamine Cohort study aromatic amino acids metabolites Introduction [Rationale and background] Cardiovascular disease is the leading cause ... US and worldwide [1] , substantially contributes to excess health system costs [2] . Though traditional risk factors ...- 2024-12-02 11:13
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ABI; PAD; Inflammation Background and Rationale Peripheral artery disease (PAD) is a prevalent cardiovascular condition ... (1) . It is associated with significant morbidity and mortality, leading to impaired limb function and ...- 2024-12-13 15:43 - 3 comments
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... interventions are urgently needed for Alzheimer’s disease (AD) and related dementias (ADRD). ADRD is highly heterogeneous ... diastolic blood pressure, eGFR, smoking, education, chronic health conditions adjusted individually (e.g., diabetes, ...- 2024-12-02 21:45
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... omega-6 to omega-3 fatty acids ratio from food intake and the risk of major depressive disorder (MDD) (Davyson et ... prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, ... esters, or triglyceride), erythrocyte (total or phospholipids), and adipose tissue; all should be expressed as ...- 2024-12-06 13:31
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... is associated with an acute decline in cognitive function and also accelerated years-long cognitive decline. 1 Stroke ... 2 Interventions to prevent post-stroke cognitive decline and dementia are needed. Observational studies have shown ... are associated with greater post-stroke cognitive decline and dementia risks, suggesting that VRF interventions are ...- 2024-12-06 06:35 - 2 comments
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... phenylacetylglutamine 1. Introduction [Rationale and background]: Type 2 diabetes has reached epidemic ... that the gut microbiome can influence cardiometabolic health. The composition of the gut microbiota is associated ... and a liver enzyme, is associated with cardiovascular diseases 12-14 and with levels of fasting insulin 15 . ...- 2024-12-20 15:00
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... are the first occurrence of atrial fibrillation (AF) and AF related stroke/TIA among those with AF. ... to discover mechanisms of pathogenesis in cardiovascular disease (CVD). Recently, the gut microbial product ... to adrenergic receptor agonists such as isoproterenol and epinephrine and was subsequently found to be able to ...- 2024-12-20 06:16 - 3 comments
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... death sudden cardiac arrest. Introduction (Background and rationale) In the last several years a mechanistic link between a Western diet and the development of cardiovascular disease has been identified via the ingestion of ...- 2024-12-19 17:59 - 1 comment