Abstract sUMOD and all-cause mortality, heart failure and cardiovascular disease Background: Uromodulin is released by renal tubular cells into the serum (sUMOD) and urine. Lower urine UMOD has been linked to ...
mobility limitation Risk model genetic factors ... subsequent disability. 2 However, the risk of developing mobility limitation over time in older adults is not well ... been systematically evaluated. We propose to develop a risk model for mobility limitation using data from many of the ...
Background: Urinary uromodulin (uUMOD) is the most commonly secreted tubular protein in ... Genetic studies demonstrate that abnormalities in the UMOD gene are associated with risk of chronic kidney disease. ...
... Muscle mass and strength cut-points associated with mobility limitation in older adults (U01-AG051421) , also ... risk of mobility disability. We will determine whether modified metrics of muscle mass and muscle strength, which ... Aim 1b. To determine whether composite, multi-component models that include both muscle mass and strength are more ...
... We aimed to develop a two-step shared parameter model to impute status and onset time in the Cardiovascular ... Health Study (CHS). Methods We used a linear mixed effects model to estimate individual cognitive trajectories in the ... the estimates as covariates in an accelerated failure time model used to impute time to incident dementia in the CHS ...
Background: Laboratory studies suggest that urinary uromodulin (uUMOD), the most common protein in the urine of healthy ... are lacking. Methods: We assessed the relationship of uUMOD with incident UTI events in 953 participants enrolled in ...
... between NEFAs and incident frailty, disability, and mobility limitation in a population-based cohort of elders. ... limitation annually. We used ordinal logistic regression to model incident frailty, linear regression to model components of frailty, and Cox regression to model ...
uromodulin fractures calcium BONE DENSITY Introduction [Rationale and background]: Urinary uromodulin, also known as Tamm-Horsfall protein, is a 95-kDa ... urinary protein among healthy adults (20-70 mg/day). Uromodulin forms a gel on the surface of the thick ascending ...
hemoglobin healthy aging functional dependence frailty cognitive ... defined by World Health Organization (WHO) criteria. We modeled hemoglobin decline in two ways: (1) per each 1 g/dL ... defined by World Health Organization (WHO) criteria. We modeled hemoglobin decline in two ways: (1) per each 1 g/dL ...
uromodulin tamm-horsfall protein Infection hospitalization ... Introduction [Rationale and background]: Urine uromodulin (uUMOD), also known as Tamm-Horsfall protein, is a ... is protective in the setting of sepsis due to a polymicrobial infection. In one small case-control study of 91 ...