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2025

Roselli C, Surakka I, Olesen MS, Sveinbjornsson G, Marston NA, Choi SHoan, Holm H, Chaffin M, Gudbjartsson D, Hill MC, et al. Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases. Nat Genet. 2025 ;57(3):539-547.

Hu Y, Haessler J, Lundin JI, Darst BF, Whitsel EA, Grove M, Guan W, Xia R, Szeto M, Raffield LM, et al. Methylome-wide association analyses of lipids and modifying effects of behavioral factors in diverse race and ethnicity participants. Clin Epigenetics. 2025 ;17(1):54.

Bene-Alhasan Y, Shitole SG, Bůzková P, Hirsch CH, Ix JH, Kizer JR, Siscovick DS, Matthan NR, Lichtenstein AH, Djoussé L, et al. Non-Esterified Fatty Acid Profiles and Cause-Specific Mortality: The Cardiovascular Health Study. J Clin Endocrinol Metab. 2025 .

Bortnick AE, Austin TR, Hamerton E, Gudmundsdottir V, Emilsson V, Jennings LL, Gudnason V, Owens DS, Massera D, Dufresne L, et al. Plasma Proteomic Assessment of Calcific Aortic Valve Disease in Older Adults. J Am Heart Assoc. 2025 ;14(5):e036336.

Fohner AE, Sitlani CM, Jayadev S, Bis JC, Trittschuh EH, Lopez OL, Tracy RP, Psaty BM, Longstreth WT, Seshadri S. Plasma TAR DNA-binding protein 43 (TDP-43) levels in a population-based cohort of older adults: The cardiovascular health study. J Alzheimers Dis. 2025 :13872877251334820.

Kurniansyah N, Strausz SJ, Chittoor G, Gupta S, Justice AE, Hrytsenko Y, Keenan BT, Cade BE, Spitzer BW, Wang H, et al. Polygenic scores for obstructive sleep apnoea reveal pathways contributing to cardiovascular disease. EBioMedicine. 2025 ;117:105790.

Zewdie HY, Fahey CA, Harrington AL, Hart JE, Biggs ML, McClure LA, Whitsel EA, Kaufman JD, Hajat A. Racial residential segregation is associated with ambient air pollution exposure after adjustment for multilevel sociodemographic factors: Evidence from eight US-based cohorts. Environ Epidemiol. 2025 ;9(1):e367.

Georgakis MK, Malik R, Bounkari OEl, Hasbani NR, Li J, Huffman JE, Shakt G, Tack RWP, Kimball TN, Asare Y, et al. Rare damaging CCR2 variants are associated with lower lifetime cardiovascular risk. Genome Med. 2025 ;17(1):27.

Yang D, Zhou D, Cai S, Gan Z, Pencina M, Avillach P, Cai T, Hong C. Robust Automated Harmonization of Heterogeneous Data Through Ensemble Machine Learning: Algorithm Development and Validation Study. JMIR Med Inform. 2025 ;13:e54133.

Grasset L, Bis JC, Frenzel S, Kojis D, Simino J, Yaqub A, Beiser A, Berr C, Bressler J, Bülow R, et al. Selected social and lifestyle correlates of brain health markers: the Cross-Cohort Collaboration Consortium. Alzheimers Dement. 2025 ;21(4):e70148.

Choi SHoan, Jurgens SJ, Xiao L, Hill MC, Haggerty CM, Sveinbjörnsson G, Morrill VN, Marston NA, Weng L-C, Pirruccello JP, et al. Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk. Nat Genet. 2025 ;57(3):548-562.

Li X, Chen H, Selvaraj MSunitha, Van Buren E, Zhou H, Wang Y, Sun R, McCaw ZR, Yu Z, Jiang M-Z, et al. A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies. Nat Comput Sci. 2025 ;5(2):125-143.

Feinberg A, Rebholz CM, Lemaitre RN, Fretts AM, Wiggins K, Sotoodehnia N, Psaty BM, Kim H. Ultra-processed foods, plant and animal sources, and all-cause, cardiovascular, and cancer mortality in older adults in the United States: results from the Cardiovascular Health Study. Am J Clin Nutr. 2025 .

Shade LMp, Sharifitabar M, Beiser A, Satizabal CL, Mosley TH, Curran JE, Bressler J, Heckbert SR, Hughes TM, Austin TR, et al. Whole genome sequence association analysis of brain structural volume measures in the NHLBI TOPMed Program highlights novel loci in diverse participants. medRxiv. 2025 .

Zhang X, Brody JA, Graff M, Highland HM, Chami N, Xu H, Wang Z, Ferrier KR, Chittoor G, Josyula NShilpa, et al. Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele. Nat Commun. 2025 ;16(1):3470.

Heath A, M McNerney W, Yesavage J. Whole Genome Variable Number Tandem Repeat Analysis in Alzheimer Disease. Neurol Genet. 2025 ;11(2):e200241.

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