You are here
Gait speed and survival in older adults.
Tuesday,2012-11-06 12:25 America/Los_Angeles — eenright
| Title | Gait speed and survival in older adults. |
| Publication Type | Journal Article |
| Year of Publication | 2011 |
| Authors | Studenski, S, Perera, S, Patel, K, Rosano, C, Faulkner, K, Inzitari, M, Brach, J, Chandler, J, Cawthon, P, Connor, EBarrett, Nevitt, M, Visser, M, Kritchevsky, S, Badinelli, S, Harris, T, Newman, AB, Cauley, J, Ferrucci, L, Guralnik, J |
| Journal | JAMA |
| Volume | 305 |
| Issue | 1 |
| Pagination | 50-8 |
| Date Published | 2011 Jan 05 |
| ISSN | 1538-3598 |
| Keywords | Aged, Cohort Studies, Female, Gait, Geriatric Assessment, Humans, Life Expectancy, Male, Survival Analysis, United States |
| Abstract | <p><b>CONTEXT: </b>Survival estimates help individualize goals of care for geriatric patients, but life tables fail to account for the great variability in survival. Physical performance measures, such as gait speed, might help account for variability, allowing clinicians to make more individualized estimates.</p><p><b>OBJECTIVE: </b>To evaluate the relationship between gait speed and survival.</p><p><b>DESIGN, SETTING, AND PARTICIPANTS: </b>Pooled analysis of 9 cohort studies (collected between 1986 and 2000), using individual data from 34,485 community-dwelling older adults aged 65 years or older with baseline gait speed data, followed up for 6 to 21 years. Participants were a mean (SD) age of 73.5 (5.9) years; 59.6%, women; and 79.8%, white; and had a mean (SD) gait speed of 0.92 (0.27) m/s.</p><p><b>MAIN OUTCOME MEASURES: </b>Survival rates and life expectancy.</p><p><b>RESULTS: </b>There were 17,528 deaths; the overall 5-year survival rate was 84.8% (confidence interval [CI], 79.6%-88.8%) and 10-year survival rate was 59.7% (95% CI, 46.5%-70.6%). Gait speed was associated with survival in all studies (pooled hazard ratio per 0.1 m/s, 0.88; 95% CI, 0.87-0.90; P < .001). Survival increased across the full range of gait speeds, with significant increments per 0.1 m/s. At age 75, predicted 10-year survival across the range of gait speeds ranged from 19% to 87% in men and from 35% to 91% in women. Predicted survival based on age, sex, and gait speed was as accurate as predicted based on age, sex, use of mobility aids, and self-reported function or as age, sex, chronic conditions, smoking history, blood pressure, body mass index, and hospitalization.</p><p><b>CONCLUSION: </b>In this pooled analysis of individual data from 9 selected cohorts, gait speed was associated with survival in older adults.</p> |
| DOI | 10.1001/jama.2010.1923 |
| Alternate Journal | JAMA |
| PubMed ID | 21205966 |
| PubMed Central ID | PMC3080184 |
| Grant List | P30 AG024827 / AG / NIA NIH HHS / United States UL1 TR000005 / TR / NCATS NIH HHS / United States K07 AG023641-05 / AG / NIA NIH HHS / United States K07 AG023641 / AG / NIA NIH HHS / United States / / Intramural NIH HHS / United States P30 AG024827-08 / AG / NIA NIH HHS / United States AG023641 / AG / NIA NIH HHS / United States AG024827 / AG / NIA NIH HHS / United States P30 AG021332 / AG / NIA NIH HHS / United States |