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Association Between 6-Minute Walk Test and All-Cause Mortality, Coronary Heart Disease-Specific Mortality, and Incident Coronary Heart Disease.
Monday,2014-05-05 13:57 America/Los_Angeles — poolea2
| Title | Association Between 6-Minute Walk Test and All-Cause Mortality, Coronary Heart Disease-Specific Mortality, and Incident Coronary Heart Disease. |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Yazdanyar, A, Aziz, MM, Enright, PL, Edmundowicz, D, Boudreau, R, Sutton-Tyrell, K, Kuller, L, Newman, AB |
| Journal | J Aging Health |
| Volume | 26 |
| Issue | 4 |
| Pagination | 583-599 |
| Date Published | 2014 Jun |
| ISSN | 1552-6887 |
| Abstract | <p><b>OBJECTIVE: </b>To examine the association between 6-min walk test (6 MWT) performance and all-cause mortality, coronary heart disease mortality, and incident coronary heart disease in older adults.</p><p><b>METHOD: </b>We conducted a time-to-event analysis of 1,665 Cardiovascular Health Study participants without prevalent cardiovascular disease with a 6 MWT.</p><p><b>RESULTS: </b>During a mean follow-up of 8 years, there were 305 incident coronary heart disease events, and 504 deaths of which 100 were coronary heart disease-related deaths. The 6 MWT performance in the shortest two distance quintiles was associated with increased risk of all-cause mortality (290-338 m: hazard ratio [HR] = 1.7; 95% confidence interval [CI] = [1.2, 2.5]; <290 m: HR = 2.1; 95% CI = [1.4, 3.0]). The adjusted risk of coronary heart disease mortality incident events among those with a 6 MWT < 290 m was not significant.</p><p><b>DISCUSSION: </b>Performance on the 6 MWT is independently associated with all-cause mortality and is of prognostic utility in community-dwelling older adults.</p> |
| DOI | 10.1177/0898264314525665 |
| Alternate Journal | J Aging Health |
| PubMed ID | 24695552 |
| PubMed Central ID | PMC4485950 |
| Grant List | P30 AG024827 / AG / NIA NIH HHS / United States R01 AG023629 / AG / NIA NIH HHS / United States T32 AG000181 / AG / NIA NIH HHS / United States |