... discussion of HRFAs in the epidemiological literature, and present a variant of the random forest algorithm that ... data from the baseline examination of the Cardiovascular Health Study (1989-1993), the Health, Aging, and Body ... HRFAs have the potential to improve our understanding of disease mechanisms in diverse populations, and guide the ...
... our systematic review on the relationship between vitamin D and memory and examined this association in two prospective ... We included 1,291 participants from the US Cardiovascular Health Study (CHS) and 915 participants from the Dutch ... associated with a greater risk of stroke, cardiovascular disease, type 2 diabetes and mortality.[2–5] ...
... dysfunction is a core component of the aging process and may play a key role in atherosclerotic cardiovascular disease (CVD). mtDNA copy number (mtDNA-CN), which ... from three prospective cohort studies—Cardiovascular Health Study (CHS), Atherosclerosis Risk in Communities ...
Background: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in patients with chronic kidney disease (CKD). ... be important for developing effective strategies to improve health outcomes. Methods: We pooled participants without ...
... highly prevalent disorder leading to heart failure, stroke, and death. Enhanced understanding of modifiable risk factors ... finding by Selmer et al is the inclusion of a relatively healthy population with less other risk factors for AF and ... failure Other (clinical) characteristics at baseline: Serum lipids (total cholesterol, HDL, LDL) BMI Hypertension/ ...
... TGF-β levels may be a risk factor for chronic kidney disease (CKD) in older adults. It is unknown if increased ... who participated in the 1996/97 visit of the Cardiovascular Health Study (CHS). Prevalent CKD was defined as eGFR< 60 ... the participants was 78 ± 5 years, 40% (n=692) were male, and 22% (n=383) were black. 436 participants (25.3%) had ...
... epidemiology heart failure cognitive decline Background and Rationale Though ambient air pollution exposure is an ... The extensive and longitudinal data from the Cardiovascular Health Study (CHS) currently offers availability of measures ... structure and function, multiple biomarkers of cardiac disease, as well as over 25 years of prospective events ...
mitochondria 1. Introduction [Rationale and background]:Energy has been hypothesized to be central to health in later life (Ruggiero C, Ferrucci L, 2006)however ... many of the clinical problems observed in age-related diseaseand frailty, including movement disorders and muscle ...
... to coordinate movement, memory, motivation, reinforcement and learning. To investigate how common genetic variants ... studies (GWAS) of the volumes of seven subcortical regions and intracranial volume, derived from magnetic resonance ... in intracerebral hemorrhage (ch1q22), Huntington’s disease (chr2p21), neuro-inflammation (chr2p21), ...