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... Muscle mass and strength cut-points associated with mobility limitation in older adults (U01-AG051421) , also ... risk of mobility disability. We will determine whether modified metrics of muscle mass and muscle strength, which ... Aim 1b. To determine whether composite, multi-component models that include both muscle mass and strength are more ...- 2016-01-08 16:25 - 4 comments
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uromodulin fractures calcium BONE DENSITY Introduction [Rationale and background]: Urinary uromodulin, also known as Tamm-Horsfall protein, is a 95-kDa ... urinary protein among healthy adults (20-70 mg/day). Uromodulin forms a gel on the surface of the thick ascending ...- 2016-06-06 19:52 - 1 comment
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... to another. The final product will be a micro-simulation model that will allow evaluation of hypothesized trials, ... from multiple observational studies to create and validate models for the impact of interventions on glycemic control ... be two separate papers). Aim 3. Develop a simulation model for cardiovascular disease risk and dementia outcomes ...- 2016-12-29 10:52 - 2 comments
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... caused by defective production of one or more globin chains of hemoglobin also have chronic bone marrow ... been as well studied in humans. Pre-clinical work in animal models has shown the relationship between hematopoiesis and ... We will consider covariates for inclusion in multivariable models if there are differences in Hgb category in ...- 2016-03-21 14:38 - 4 comments
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... independent of BMD. We hypothesized that lower hemoglobin (Hgb) levels and decreases in Hgb are associated with ... Medicare claims data. Sex-specific Cox proportional-hazards models estimated hazard ratios (HR) and 95% confidence ... those with greatest Hgb decrease (vs. others). Nested models sequentially adjusted for 1) age, race and study ...- 2016-11-07 11:33 - 2 comments
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... TYPE OF FATAL CHD mechan80 MECHANISM OF CARDIAC DEATH anblmod ANG MODIFIED BL STAT incang INCIDENT ANGINA defprang DEFINITE OR ... INCIDENT BYPASS SURGERY ttobyps TIME TO BYPASS SURGERY chblmod CHF MODIFIED BL STAT incchf INCIDENT CHF defprchf ...- 2016-07-26 13:44
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... Similar to prior studies, 12 change in hs-cTnT will be modeled using two different approaches: 1) Change as a ... defined as incident stable. Statistical Analysis Aim 1 Model 1 Multivariable linear regression wi th adjust ments ... adjustments for standard covariates will also be preformed. Model 2 Multivariable linear regression with adjustments for ...- 2016-07-13 13:48 - 4 comments
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... with mortality and disability. Results: The unidimensional model fit the data satisfactorily; similar factor structure ... removing the ceiling effect encountered in the original FP model. Some of these advantages have been demonstrated by a ... In addition, existing validations rarely report indices of model performance except for the c statistic, which may lead ...- 2016-02-10 08:45 - 1 comment
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... from a median 13 years of follow-up. Risk prediction models using cumulative means of the repeat measures and summary measures from longitudinal modelling of the repeat measures were compared to models using measures from a single time point. Risk ...- 2016-05-26 12:38
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... ≥65 years. Cognitive function was assessed annually with Modified Mini-Mental State Exam (3MS) and Digit Symbol Substitution Test (DSST). We used linear mixed models to estimate the individual and joint associations of epilepsy and VRFs with cognitive decline by modeling epilepsy × VRF interactions one by one, each ...- 2016-11-04 12:47 - 4 comments