... analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) ...
Stroke has multiple etiologies but the specific causal genes and pathways are largely unknown. We conducted a ... meta-analysis in 520,000 individuals (67,162 cases and 454,450 controls) and discovered 22 novel stroke risk loci bringing the total ...
... Americans as well as the SNP-by-drug interaction on LVM and relative wall thickness (RWT) in five cohorts with a ... (TDs), angiotensin converting enzyme inhibitors (ACE-Is), and dihydropyridine calcium channel blockers (dCCBs). TDs, ACE-Is, and dCCBs were compared in a pairwise manner. Diastolic ...
Discovery and fine-mapping of loci associated with monounsaturated ... fatty acids through trans-ethnic meta-analysis in Chinese and European populations. ...