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Journal Article
Fornage M, Y Chiang A, O'Meara ES, Psaty BM, Reiner AP, Siscovick DS, Tracy RP, Longstreth WT. Biomarkers of Inflammation and MRI-Defined Small Vessel Disease of the Brain: The Cardiovascular Health Study. Stroke. 2008 ;39(7):1952-9.
Leung LY, Bartz TM, Rice K, Floyd J, Psaty B, Gutierrez J, Longstreth WT, Mukamal KJ. Blood Pressure and Heart Rate Measures Associated With Increased Risk of Covert Brain Infarction and Worsening Leukoaraiosis in Older Adults. Arterioscler Thromb Vasc Biol. 2017 ;37(8):1579-1586.
Kaplan RC, Tirschwell DL, Longstreth WT, Manolio TA, Heckbert SR, LeValley AJ, Lefkowitz D, El-Saed A, Psaty BM. Blood pressure level and outcomes in adults aged 65 and older with prior ischemic stroke. J Am Geriatr Soc. 2006 ;54(9):1309-16.
Suchy-Dicey AM, Wallace ER, Mitchell SVElkind, Aguilar M, Gottesman RF, Rice K, Kronmal R, Psaty BM, Longstreth WT. Blood pressure variability and the risk of all-cause mortality, incident myocardial infarction, and incident stroke in the cardiovascular health study. Am J Hypertens. 2013 ;26(10):1210-7.
Longstreth WT. Brain abnormalities in the elderly: frequency and predictors in the United States (the Cardiovascular Health Study). Cardiovascular Health Study Collaborative Research Group. J Neural Transm Suppl. 1998 ;53:9-16.
Longstreth WT, Diehr PH, Yee LM, Newman AB, Beauchamp NJ. Brain imaging findings in elderly adults and years of life, healthy life, and able life over the ensuing 16 years: the Cardiovascular Health Study. J Am Geriatr Soc. 2014 ;62(10):1838-43.
Folsom AR, Yatsuya H, Psaty BM, Shahar E, Longstreth WT. Carotid intima-media thickness, electrocardiographic left ventricular hypertrophy, and incidence of intracerebral hemorrhage. Stroke. 2011 ;42(11):3075-9.
Georgakis MK, Malik R, Hasbani NR, Shakt G, Morrison AC, Tsao NL, Judy R, Mitchell BD, Xu H, Montasser ME, et al. Carriers of rare damaging genetic variants are at lower risk of atherosclerotic disease. medRxiv. 2023 .
Gilsanz P, Kubzansky LD, Tchetgen EJTchetgen, Wang Q, Kawachi I, Patton KK, Fitzpatrick AL, Kop WJ, Longstreth WT, M Glymour M. Changes in Depressive Symptoms and Subsequent Risk of Stroke in the Cardiovascular Health Study. Stroke. 2016 .
Kalani R, Bartz TM, Suchy-Dicey A, Elkind MSV, Psaty BM, Leung LY, Rice K, Tirschwell D, Longstreth WT. Cholesterol Variability and Cranial Magnetic Resonance Imaging Findings in Older Adults: The Cardiovascular Health Study. Stroke. 2020 ;51(1):69-74.
Longstreth WT, Arnold AM, Manolio TA, Burke GL, Bryan N, Jungreis CA, O'Leary D, Enright PL, Fried L. Clinical correlates of ventricular and sulcal size on cranial magnetic resonance imaging of 3,301 elderly people. The Cardiovascular Health Study. Collaborative Research Group. Neuroepidemiology. 2000 ;19(1):30-42.
Longstreth WT, Manolio TA, Arnold A, Burke GL, Bryan N, Jungreis CA, Enright PL, O'Leary D, Fried L. Clinical correlates of white matter findings on cranial magnetic resonance imaging of 3301 elderly people. The Cardiovascular Health Study. Stroke. 1996 ;27(8):1274-82.
Yue NC, Longstreth WT, Elster AD, Jungreis CA, O'Leary DH, Poirier VC. Clinically serious abnormalities found incidentally at MR imaging of the brain: data from the Cardiovascular Health Study. Radiology. 1997 ;202(1):41-6.
Longstreth WT, Diehr P, Manolio TA, Beauchamp NJ, Jungreis CA, Lefkowitz D. Cluster analysis and patterns of findings on cranial magnetic resonance imaging of the elderly: the Cardiovascular Health Study. Arch Neurol. 2001 ;58(4):635-40.
Rohmann JL, Longstreth WT, Cushman M, Fitzpatrick AL, Heckbert SR, Rice K, Rosendaal FR, Sitlani CM, Psaty BM, Siegerink B. Coagulation factor VIII, white matter hyperintensities and cognitive function: Results from the Cardiovascular Health Study. PLoS One. 2020 ;15(11):e0242062.
Olson NC, Butenas S, Lange LA, Lange EM, Cushman M, Jenny NS, Walston J, Souto JC, Soria JM, Chauhan G, et al. Coagulation factor XII genetic variation, ex vivo thrombin generation, and stroke risk in the elderly: results from the Cardiovascular Health Study. J Thromb Haemost. 2015 ;13(10):1867-77.
Welmerink DB, Longstreth WT, Lyles MF, Fitzpatrick AL. Cognition and the risk of hospitalization for serious falls in the elderly: results from the Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci. 2010 ;65(11):1242-9.
S Johnston C, O'Meara ES, Manolio TA, Lefkowitz D, O'Leary DH, Goldstein S, Carlson MC, Fried LP, Longstreth WT. Cognitive impairment and decline are associated with carotid artery disease in patients without clinically evident cerebrovascular disease. Ann Intern Med. 2004 ;140(4):237-47.
Sargurupremraj M, Soumaré A, Bis JC, Surakka I, Jürgenson T, Joly P, Knol MJ, Wang R, Yang Q, Satizabal CL, et al. Complexities of cerebral small vessel disease, blood pressure, and dementia relationship: new insights from genetics. medRxiv. 2023 .
Seliger SL, Longstreth WT, Katz R, Manolio T, Fried LF, Shlipak M, Stehman-Breen CO, Newman A, Sarnak M, Gillen DL, et al. Cystatin C and subclinical brain infarction. J Am Soc Nephrol. 2005 ;16(12):3721-7.
Dhamoon MS, Longstreth WT, Bartz TM, Kaplan RC, Elkind MSV. Disability Trajectories Before and After Stroke and Myocardial Infarction: The Cardiovascular Health Study. JAMA Neurol. 2017 ;74(12):1439-1445.
Elkins JS, Longstreth WT, Manolio TA, Newman AB, Bhadelia RA, Johnston SC. Education and the cognitive decline associated with MRI-defined brain infarct. Neurology. 2006 ;67(3):435-40.
Yang Y, Knol MJ, Wang R, Mishra A, Liu D, Luciano M, Teumer A, Armstrong N, Bis JC, Jhun MA, et al. Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI. Brain. 2022 .
Choi H, Elkind MSV, Longstreth WT, Boehme AK, Hafen R, Hoyt EJ, Thacker EL. Epilepsy, Vascular Risk Factors, and Cognitive Decline in Older Adults: The Cardiovascular Health Study. Neurology. 2022 ;99(21):e2346-e2358.
Jian X, Satizabal CL, Smith AV, Wittfeld K, Bis JC, Smith JA, Hsu F-C, Nho K, Hofer E, Hagenaars SP, et al. Exome Chip Analysis Identifies Low-Frequency and Rare Variants in for White Matter Hyperintensities on Brain Magnetic Resonance Imaging. Stroke. 2018 .

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