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Journal Article

Irie F, Fitzpatrick AL, Lopez OL, Kuller LH, Peila R, Newman AB, Launer LJ. Enhanced risk for Alzheimer disease in persons with type 2 diabetes and APOE epsilon4: the Cardiovascular Health Study Cognition Study. Arch Neurol. 2008 ;65(1):89-93.

Boyle CP, Raji CA, Erickson KI, Lopez OL, Becker JT, H Gach M, Kuller LH, Longstreth W, Carmichael OT, Riedel BC, et al. Estrogen, brain structure, and cognition in postmenopausal women. Hum Brain Mapp. 2020 .

Lopez OL, Kuller LH, Fitzpatrick A, Ives D, Becker JT, Beauchamp N. Evaluation of dementia in the cardiovascular health cognition study. Neuroepidemiology. 2003 ;22(1):1-12.

Laugsand LE, Ix JH, Bartz TM, Djoussé L, Kizer JR, Tracy RP, Dehghan A, Rexrode K, Lopez OL, Rimm EB, et al. Fetuin-A and risk of coronary heart disease: A Mendelian randomization analysis and a pooled analysis of AHSG genetic variants in 7 prospective studies. Atherosclerosis. 2015 ;243(1):44-52.

Rosano C, Aizenstein HJ, Wu M, Newman AB, Becker JT, Lopez OL, Kuller LH. Focal atrophy and cerebrovascular disease increase dementia risk among cognitively normal older adults. J Neuroimaging. 2007 ;17(2):148-55.

Satizabal CL, Adams HHH, Hibar DP, White CC, Knol MJ, Stein JL, Scholz M, Sargurupremraj M, Jahanshad N, Roshchupkin GV, et al. Genetic architecture of subcortical brain structures in 38,851 individuals. Nat Genet. 2019 ;51(11):1624-1636.

Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nat Genet. 2019 ;51(3):414-430.

Escott-Price V, Bellenguez C, San Wang L-, Choi S-H, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, et al. Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease. PLoS One. 2014 ;9(6):e94661.

Seshadri S, Fitzpatrick AL, Ikram AM, DeStefano AL, Gudnason V, Boada M, Bis JC, Smith AV, Carassquillo MM, Lambert JCharles, et al. Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA. 2010 ;303(18):1832-40.

Fornage M, Debette S, Bis JC, Schmidt H, Ikram AM, Dufouil C, Sigurdsson S, Lumley T, DeStefano AL, Fazekas F, et al. Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium. Ann Neurol. 2011 ;69(6):928-39.

Ikram AM, Seshadri S, Bis JC, Fornage M, DeStefano AL, Aulchenko YS, Debette S, Lumley T, Folsom AR, van den Herik EG, et al. Genomewide association studies of stroke. N Engl J Med. 2009 ;360(17):1718-28.

Vojinovic D, Adams HH, Jian X, Yang Q, Smith AVernon, Bis JC, Teumer A, Scholz M, Armstrong NJ, Hofer E, et al. Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume. Nat Commun. 2018 ;9(1):3945.

Debette S, Verbaas CAIbrahim, Bressler J, Schuur M, Smith A, Bis JC, Davies G, Wolf C, Gudnason V, Chibnik LB, et al. Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. Biol Psychiatry. 2015 ;77(8):749-63.

Adhikari S, Lecci F, Becker JT, Junker BW, Kuller LH, Lopez OL, Tibshirani RJ. High-dimensional longitudinal classification with the multinomial fused lasso. Stat Med. 2019 .

Lee C, Lopez OL, Becker JT, Raji C, Dai W, Kuller LH, H Gach M. Imaging cerebral blood flow in the cognitively normal aging brain with arterial spin labeling: implications for imaging of neurodegenerative disease. J Neuroimaging. 2009 ;19(4):344-52.

Fitzpatrick AL, Kuller LH, Ives DG, Lopez OL, Jagust W, Breitner JCS, Jones B, Lyketsos C, Dulberg C. Incidence and prevalence of dementia in the Cardiovascular Health Study. J Am Geriatr Soc. 2004 ;52(2):195-204.

Lopez OL, Kuller LH, Becker JT, Dulberg C, Sweet RA, H Gach M, DeKosky ST. Incidence of dementia in mild cognitive impairment in the cardiovascular health study cognition study. Arch Neurol. 2007 ;64(3):416-20.

Lopez OL, Becker JT, Chang Y-F, Sweet RA, DeKosky ST, Gach MH, Carmichael OT, McDade E, Kuller LH. Incidence of mild cognitive impairment in the Pittsburgh Cardiovascular Health Study-Cognition Study. Neurology. 2012 ;79(15):1599-606.

Fan KH, Francis L, M Aslam M, Bedison MA, Lawrence E, Acharya V, Snitz BE, Ganguli M, DeKosky ST, Lopez OL, et al. Investigation of the independent role of a rare APOE variant (L28P; APOE*4Pittsburgh) in late-onset Alzheimer disease. Neurobiol Aging. 2023 ;122:107-111.

Chwa WJong, Lopez OL, Longstreth WT, Dai W, Raji CA. Longitudinal Patterns of Brain Changes in a Community Sample in Relation to Aging and Cognitive Status. J Alzheimers Dis. 2023 .

Raji CA, Merrill DA, Eyre H, Mallam S, Torosyan N, Erickson KI, Lopez OL, Becker JT, Carmichael OT, H Gach M, et al. Longitudinal Relationships between Caloric Expenditure and Gray Matter in the Cardiovascular Health Study. J Alzheimers Dis. 2016 ;52(2):719-29.

Thirumala PD, Reddy RP, Lopez OL, Chang Y-F, Becker JT, Kuller LH. Long-term cognitive decline and mortality after carotid endarterectomy. Clin Neurol Neurosurg. 2020 ;194:105823.

Rosano C, Chang Y-F, Kuller LH, Guralnik JM, Studenski SA, Aizenstein HJ, Gianaros PJ, Lopez OL, Longstreth WT, Newman AB. Long-term survival in adults 65 years and older with white matter hyperintensity: association with performance on the digit symbol substitution test. Psychosom Med. 2013 ;75(7):624-31.

Hughes TM, Kuller LH, Lopez OL, Becker JT, Evans RW, Sutton-Tyrrell K, Rosano C. Markers of cholesterol metabolism in the brain show stronger associations with cerebrovascular disease than Alzheimer's disease. J Alzheimers Dis. 2012 ;30(1):53-61.

Fitzpatrick AL, Kuller LH, Lopez OL, Diehr P, O'Meara ES, Longstreth WT, Luchsinger JA. Midlife and late-life obesity and the risk of dementia: cardiovascular health study. Arch Neurol. 2009 ;66(3):336-42.

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