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2021

Bressler J, Davies G, Smith AV, Saba Y, Bis JC, Jian X, Hayward C, Yanek L, Smith JA, Mirza SS, et al. Association of low-frequency and rare coding variants with information processing speed. Transl Psychiatry. 2021 ;11(1):613.

Nair N, Vittinghoff E, Pletcher MJ, Oelsner EC, Allen NB, Ndumele CE, West NA, Strotmeyer ES, Mukamal KJ, Siscovick DS, et al. Associations of Body Mass Index and Waist Circumference in Young Adulthood with Later Life Incident Diabetes. J Clin Endocrinol Metab. 2021 ;106(12):e5011-e5020.

Harris WS, Tintle NL, Imamura F, Qian F, Korat AVArdisson, Marklund M, Djoussé L, Bassett JK, Carmichael P-H, Chen Y-Y, et al. Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies. Nat Commun. 2021 ;12(1):2329.

Stein PK, Bůzková P, Fink HA, Robbins JA, Mukamal KJ, Cauley JA, Carbone L, Elam R, McMillan DW, Valderrabano R, et al. Cardiovascular autonomic nervous system function and hip fracture risk: the Cardiovascular Health Study. Arch Osteoporos. 2021 ;16(1):163.

Yaffe K, Vittinghoff E, Hoang T, Matthews K, Golden SH, Hazzouri AZeki Al. Cardiovascular Risk Factors Across the Life Course and Cognitive Decline: A Pooled Cohort Study. Neurology. 2021 ;96(17):e2212-e2219.

Brenowitz WD, Hazzouri AZeki Al, Vittinghoff E, Golden SH, Fitzpatrick AL, Yaffe K. Depressive Symptoms Imputed Across the Life Course Are Associated with Cognitive Impairment and Cognitive Decline. J Alzheimers Dis. 2021 ;83(3):1379-1389.

Goodrich JK, Singer-Berk M, Son R, Sveden A, Wood J, England E, Cole JB, Weisburd B, Watts N, Caulkins L, et al. Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes. Nat Commun. 2021 ;12(1):3505.

Djoussé L, Zhou G, McClelland RL, Ma N, Zhou X, Kabagambe EK, Talegawkar SA, Judd SE, Biggs ML, Fitzpatrick AL, et al. Egg consumption, overall diet quality, and risk of type 2 diabetes and coronary heart disease: A pooling project of US prospective cohorts. Clin Nutr. 2021 ;40(5):2475-2482.

Roberts JD, Vittinghoff E, Lu AT, Alonso A, Wang B, Sitlani CM, Mohammadi-Shemirani P, Fornage M, Kornej J, Brody JA, et al. Epigenetic Age and the Risk of Incident Atrial Fibrillation. Circulation. 2021 ;144(24):1899-1911.

Tin A, Schlosser P, Matias-Garcia PR, Thio CHL, Joehanes R, Liu H, Yu Z, Weihs A, Hoppmann A, Grundner-Culemann F, et al. Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus. Nat Commun. 2021 ;12(1):7173.

He Z, Liu L, Wang C, Le Guen Y, Lee J, Gogarten S, Lu F, Montgomery S, Tang H, Silverman EK, et al. Identification of putative causal loci in whole-genome sequencing data via knockoff statistics. Nat Commun. 2021 ;12(1):3152.

Schlosser P, Tin A, Matias-Garcia PR, Thio CHL, Joehanes R, Liu H, Weihs A, Yu Z, Hoppmann A, Grundner-Culemann F, et al. Meta-analyses identify DNA methylation associated with kidney function and damage. Nat Commun. 2021 ;12(1):7174.

Zhan L, Li J, Jew B, Sul JHoon. Rare variants in the endocytic pathway are associated with Alzheimer's disease, its related phenotypes, and functional consequences. PLoS Genet. 2021 ;17(9):e1009772.

Huang NK, Biggs ML, Matthan NR, Djoussé L, Longstreth WT, Mukamal KJ, Siscovick DS, Lichtenstein AH. Serum Nonesterified Fatty Acids and Incident Stroke: The CHS. J Am Heart Assoc. 2021 ;10(22):e022725.

Huang NK, Bůzková P, Matthan NR, Djoussé L, Kizer JR, Mukamal KJ, Polak JF, Lichtenstein AH. Serum Non-Esterified Fatty Acids, Carotid Artery Intima-Media Thickness and Flow-Mediated Dilation in Older Adults: The Cardiovascular Health Study (CHS). Nutrients. 2021 ;13(9).

Levine DA, Gross AL, Briceño EM, Tilton N, Giordani BJ, Sussman JB, Hayward RA, Burke JF, Hingtgen S, Elkind MSV, et al. Sex Differences in Cognitive Decline Among US Adults. JAMA Netw Open. 2021 ;4(2):e210169.

Yu B, Roberts MB, Raffield LM, Zekavat SMaryam, Nguyen NQuynh H, Biggs ML, Brown MR, Griffin G, Desai P, Correa A, et al. Supplemental Association of Clonal Hematopoiesis With Incident Heart Failure. J Am Coll Cardiol. 2021 ;78(1):42-52.

Sahni S, Dufour AB, Fielding RA, Newman AB, Kiel DP, Hannan MT, Jacques PF. Total carotenoid intake is associated with reduced loss of grip strength and gait speed over time in adults: The Framingham Offspring Study. Am J Clin Nutr. 2021 ;113(2):437-445.

Cawthon PM, Patel SM, Kritchevsky SB, Newman AB, Santanasto A, Kiel DP, Travison TG, Lane N, Cummings SR, Orwoll ES, et al. What Cut-Point in Gait Speed Best Discriminates Community-Dwelling Older Adults With Mobility Complaints From Those Without? A Pooled Analysis From the Sarcopenia Definitions and Outcomes Consortium. J Gerontol A Biol Sci Med Sci. 2021 ;76(10):e321-e327.

Hu Y, Stilp AM, McHugh CP, Rao S, Jain D, Zheng X, Lane J, de Bellefon SMéric, Raffield LM, Chen M-H, et al. Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program. Am J Hum Genet. 2021 ;108(5):874-893.

Mikhaylova AV, McHugh CP, Polfus LM, Raffield LM, Boorgula MPreethi, Blackwell TW, Brody JA, Broome J, Chami N, Chen M-H, et al. Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program. Am J Hum Genet. 2021 ;108(10):1836-1851.

2020

Katsumata Y, Fardo DW, Bachstetter AD, Artiushin SC, Wang W-X, Wei A, Brzezinski LJ, Nelson BG, Huang Q, Abner EL, et al. Alzheimer Disease Pathology-Associated Polymorphism in a Complex Variable Number of Tandem Repeat Region Within the MUC6 Gene, Near the AP2A2 Gene. J Neuropathol Exp Neurol. 2020 ;79(1):3-21.

McComish BJ, Sahebjada S, Bykhovskaya Y, Willoughby CE, Richardson AJ, Tenen A, Charlesworth JC, Macgregor S, Mitchell P, Lucas SEM, et al. Association of Genetic Variation With Keratoconus. JAMA Ophthalmol. 2020 ;138(2):174-181.

Balte PP, Chaves PHM, Couper DJ, Enright P, Jacobs DR, Kalhan R, Kronmal RA, Loehr LR, London SJ, Newman AB, et al. Association of Nonobstructive Chronic Bronchitis With Respiratory Health Outcomes in Adults. JAMA Intern Med. 2020 ;180(5):676-686.

Moll M, Sakornsakolpat P, Shrine N, Hobbs BD, DeMeo DL, John C, Guyatt AL, McGeachie MJ, Gharib SA, Obeidat M'en, et al. Chronic obstructive pulmonary disease and related phenotypes: polygenic risk scores in population-based and case-control cohorts. Lancet Respir Med. 2020 ;8(7):696-708.

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