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2023

Huffman JE, Nicolas J, Hahn J, Heath AS, Raffield LM, Yanek LR, Brody JA, Thibord F, Almasy L, Bartz TM, et al. Whole genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles. medRxiv. 2023 .

Seyerle AA, Laurie CA, Coombes BJ, Jain D, Conomos MP, Brody J, Chen M-H, Gogarten SM, Beutel KM, Gupta N, et al. Whole Genome Analysis of Venous Thromboembolism: the Trans-Omics for Precision Medicine Program. Circ Genom Precis Med. 2023 :e003532.

Armstrong ND, Srinivasasainagendra V, Ammous F, Assimes TL, Beitelshees AL, Brody J, Cade BE, Chen Y-DIda, Chen H, de Vries PS, et al. Whole genome sequence analysis of apparent treatment resistant hypertension status in participants from the Trans-Omics for Precision Medicine program. Front Genet. 2023 ;14:1278215.

Zhang X, Brody JA, Graff M, Highland HM, Chami N, Xu H, Wang Z, Ferrier K, Chittoor G, Josyula NS, et al. WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE. medRxiv. 2023 .

Jiang M-Z, Gaynor SM, Li X, Van Buren E, Stilp A, Buth E, Wang FFei, Manansala R, Gogarten SM, Li Z, et al. Whole Genome Sequencing Based Analysis of Inflammation Biomarkers in the Trans-Omics for Precision Medicine (TOPMed) Consortium. bioRxiv. 2023 .

Feofanova EV, Brown MR, Alkis T, Manuel AM, Li X, Tahir UA, Li Z, Mendez KM, Kelly RS, Qi Q, et al. Whole-Genome Sequencing Analysis of Human Metabolome in Multi-Ethnic Populations. Nat Commun. 2023 ;14(1):3111.

de Vries PS, Conomos MP, Singh K, Nicholson CJ, Jain D, Hasbani NR, Jiang W, Lee S, Cardenas CLLino, Lutz SM, et al. Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification. Nat Cardiovasc Res. 2023 ;2(12):1159-1172.

2022

Wainschtein P, Jain D, Zheng Z, Cupples AL, Shadyab AH, McKnight B, Shoemaker BM, Mitchell BD, Psaty BM, Kooperberg C, et al. Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data. Nat Genet. 2022 ;54(3):263-273.

Barasch E, Gottdiener JS, Tressel W, Bartz TM, Bůzková P, Massera D, DeFilippi C, Biggs ML, Psaty BM, Kizer JR, et al. The association of aortic valve sclerosis, aortic annulus increased reflectivity, and mitral annular calcification with subsequent aortic stenosis in older individuals. Findings from the Cardiovascular Health Study. J Am Soc Echocardiogr. 2022 .

Dobrota SD, Biggs ML, Pratt S, Popat R, Odden MC. The association of hearing problems with social network strength and depressive symptoms: the cardiovascular health study. Age Ageing. 2022 ;51(8).

Sinha A, Sitlani CM, Doyle MF, Fohner AE, Bůzková P, Floyd JS, Huber SA, Olson NC, Njoroge JN, Kizer JR, et al. Association of immune cell subsets with incident heart failure in two population-based cohorts. ESC Heart Fail. 2022 .

Barzilay JI, Bůzková P, Kuller LH, Cauley JA, Fink HA, Sheets K, Robbins JA, Carbone LD, Elam RE, Mukamal KJ. The Association of Lipids and Lipoproteins with Hip Fracture Risk the Cardiovascular Health Study. Am J Med. 2022 .

Barzilay JI, Tressel W, Biggs ML, Stein PK, Kizer JR, Shitole SG, Bene-Alhasan Y, Mukamal KJ. The Association of Measures of Cardiovascular Autonomic Function, Heart Rate, and Orthostatic Hypotension With Incident Glucose Disorders: The Cardiovascular Health Study. Diabetes Care. 2022 ;45(10):2376-2382.

Fohner AE, Bartz TM, Tracy RP, Adams HHH, Bis JC, Djoussé L, Satizabal CL, Lopez OL, Seshadri S, Mukamal KJ, et al. Association of Serum Neurofilament Light Chain Concentration and MRI Findings in Older Adults: The Cardiovascular Health Study. Neurology. 2022 ;98(9):e903-e911.

Fretts AM, Hazen SL, Jensen P, Budoff M, Sitlani CM, Wang M, Otto MC de Olive, DiDonato JA, Lee Y, Psaty BM, et al. Association of Trimethylamine N-Oxide and Metabolites With Mortality in Older Adults. JAMA Netw Open. 2022 ;5(5):e2213242.

Jin B, Capra JA, Benchek P, Wheeler N, Naj AC, Hamilton-Nelson KL, Farrell JJ, Leung YY, Kunkle B, Vadarajan B, et al. {An association test of the spatial distribution of rare missense variants within protein structures identifies Alzheimer's disease-related patterns. Genome Res. 2022 ;32:778–790.

Wilkens TL, Sørensen H, Jensen MK, Furtado JD, Dragsted LO, Mukamal KJ. Associations between Alcohol Consumption and HDL Subspecies Defined by ApoC3, ApoE and ApoJ: the Cardiovascular Health Study. Curr Probl Cardiol. 2022 ;48(1):101395.

Ahiawodzi P, Bůzková P, Lichtenstein AH, Matthan NR, Ix JH, Kizer JR, Tracy RP, Arnold A, Newman AB, Siscovick D, et al. The Associations of Individual and Subclasses of Non-Esterified Fatty Acids with Disability, and Mobility Limitation in Older Adults: the Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci. 2022 .

Smagula SF, Biggs ML, Jacob ME, Rawlings AM, Odden MC, Arnold A, Newman AB, Buysse DJ. Associations of modifiable behavioral risk factor combinations at 65-74 years old with cognitive healthspan over 20 years. Psychosom Med. 2022 .

Frenzel S, Bis JC, Gudmundsson EF, O'Donnell A, Simino J, Yaqub A, Bartz TM, Brusselle GGO, Bülow R, DeCarli CS, et al. Associations of Pulmonary Function with MRI Brain Volumes: A Coordinated Multi-Study Analysis. J Alzheimers Dis. 2022 .

Zhang L, Bartz TM, Santanasto A, Djoussé L, Mukamal KJ, Forman DE, Hirsch CH, Newman AB, Gottdiener JS, Kizer JR. Body Composition and Incident Heart Failure in Older Adults: Results From 2 Prospective Cohorts. J Am Heart Assoc. 2022 ;11(1):e023707.

Kunihiro AG, Sarrett SM, Lastwika KJ, Solan JL, Pisarenko T, Keinänen O, Rodriguez C, Taverne LR, Fitzpatrick AL, Li CI, et al. CD133 as a Biomarker for an Autoantibody-to-ImmunoPET Paradigm for the Early Detection of Small Cell Lung Cancer. J Nucl Med. 2022 ;63(11):1701-1707.

Njoroge JN, Tressel W, Biggs ML, Matsumoto AM, Smith NL, Rosenberg E, Hirsch CH, Gottdiener JS, Mukamal KJ, Kizer JR. Circulating Androgen Concentrations and Risk of Incident Heart Failure in Older Men: The Cardiovascular Health Study. J Am Heart Assoc. 2022 ;11(21):e026953.

Durda P, Raffield LM, Lange EM, Olson NC, Jenny NSwords, Cushman M, Deichgraeber P, Grarup N, Jonsson A, Hansen T, et al. Circulating Soluble CD163, Associations With Cardiovascular Outcomes and Mortality, and Identification of Genetic Variants in Older Individuals: The Cardiovascular Health Study. J Am Heart Assoc. 2022 ;11(21):e024374.

Bhattacharya R, Zekavat SM, Haessler J, Fornage M, Raffield L, Uddin MMesbah, Bick AG, Niroula A, Yu B, Gibson C, et al. Clonal Hematopoiesis Is Associated With Higher Risk of Stroke. Stroke. 2022 ;53(3):788-797.

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